Abstract
Go with the flow: An effective method for the generation and reaction of aryllithium compounds bearing an alkoxycarbonyl group is developed using microflow systems with very short residence times together with fast mixing and efficient temperature control. A wide range of alkoxycarbonyl groups including ethoxycarbonyl and methoxycarbonyl groups are tolerant of the microflow conditions. (Chemical Equation Presented)
Original language | English |
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Pages (from-to) | 7833-7836 |
Number of pages | 4 |
Journal | Angewandte Chemie - International Edition |
Volume | 47 |
Issue number | 41 |
DOIs | |
Publication status | Published - 2008 Sept 29 |
Externally published | Yes |
Keywords
- Arenes
- Electrophilic substitution
- Lithiation
- Microreactors
- Reactive intermediates
ASJC Scopus subject areas
- Catalysis
- General Chemistry