Asian consensus report on functional dyspepsia

Hiroto Miwa, Uday C. Ghoshal, Sutep Gonlachanvit, Kok Ann Gwee, Tiing Leong Ang, Full Young Chang, Kwong Ming Fock, Michio Hongo, Xiaohua Hou, Udom Kachintorn, Meiyun Ke, Kwok Hung Lai, Kwang Jae Lee, Ching Liang Lu, Sanjiv Mahadeva, Soichiro Miura, Hyojin Park, Poong Lyul Rhee, Kentaro Sugano, Ratha Korn VilaichoneBenjamin C.Y. Wong, Young-Tae Bak

    Research output: Contribution to journalArticlepeer-review

    79 Citations (Scopus)


    Background/Aims: Environmental factors such as food, lifestyle and prevalence of Helicobacter pylori infection are widely different in Asian countries compared to the West, and physiological functions and genetic factors of Asians may also be different from those of Westerners. Establishing an Asian consensus for functional dyspepsia is crucial in order to attract attention to such data from Asian countries, to articulate the experience and views of Asian experts, and to provide a relevant guide on management of functional dyspepsia for primary care physicians working in Asia. Methods: Consensus team members were selected from Asian experts and consensus development was carried out using a modified Delphi method. Consensus teams collected published papers on functional dyspepsia especially from Asia and developed candidate consensus statements based on the generated clinical questions. At the first face-to-face meeting, each statement was reviewed and e-mail voting was done twice. At the second face-to-face meeting, final voting on each statement was done using keypad voting system. A grade of evidence and a strength of recommendation were applied to each statement according to the method of the GRADE Working Group. Results: Twenty-nine consensus statements were finalized, including 7 for definition and diagnosis, 5 for epidemiology, 9 for pathophysiology and 8 for management. Algorithms for diagnosis and management of functional dyspepsia were added. Conclusions: This consensus developed by Asian experts shows distinctive features of functional dyspepsia in Asia and will provide a guide to the diagnosis and management of functional dyspepsia for Asian primary care physicians.

    Original languageEnglish
    Pages (from-to)150-168
    Number of pages19
    JournalJournal of Neurogastroenterology and Motility
    Issue number2
    Publication statusPublished - 2012 Aug 24


    • Asia
    • Diagnosis
    • Epidemiology
    • Functional dyspepsia
    • Management
    • Pathophysiology

    ASJC Scopus subject areas

    • Clinical Neurology
    • Gastroenterology


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