Assessment of adverse impacts of glyphosate-based herbicide, Excel Mera 71 by integrating multi-level biomarker responses in fishes

P. Samanta; S. Pal; A. K. Mukherjee; T. Senapati; J. Jung; A. R. Ghosh

doi:10.1007/s13762-018-2013-3

Assessment of adverse impacts of glyphosate-based herbicide, Excel Mera 71 by integrating multi-level biomarker responses in fishes

P. Samanta, S. Pal, A. K. Mukherjee, T. Senapati, J. Jung, A. R. Ghosh

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

This work was aimed to investigate the adverse impacts of Excel Mera 71 on Anabas testudineus, Heteropneustes fossilis and Oreochromis niloticus under laboratory (17.2 mg/L) and field (750 g/acre) conditions based on multiple-level integrated biomarker responses. Haematological parameters were influenced significantly and showed species specificity after Excel Mera 71 exposure under both the conditions. Physiological indices (hepato-somatic index and condition factor) showed higher values; however, hepato-somatic index induced significantly under both the conditions (p < 0.05). Total nuclear abnormalities at molecular level revealed enhanced level. Responses were more adverse in laboratory (O. niloticus > H. fossilis > A. testudineus), while total nuclear abnormalities under field showed the order as: H. fossilis (0.49 ± 0.08) > A. testudineus (0.46 ± 0.10) > O. niloticus (0.27 ± 0.05). Moreover, multi-level integrated biomarker responses displayed responses as: O. niloticus (6.97 fold) > H. fossilis (4.01 fold) > A. testudineus (2.33 fold) in laboratory; however, under field condition, responses were totally different [A. testudineus–H. fossilis (3.98 fold) > O. niloticus (3.01 fold)]. Additionally, glyphosate concentration was significantly correlated with several multi-level biomarker responses (p < 0.05). Moreover, multi-level integrated biomarker responses clearly indicated the higher impacts under laboratory experiment. Present investigation documented that multi-level integrative biomarker responses should be considered as reliable tool for assessment of herbicidal intoxication.

Original language	English
Pages (from-to)	6291-6300
Number of pages	10
Journal	International Journal of Environmental Science and Technology
Volume	16
Issue number	10
DOIs	https://doi.org/10.1007/s13762-018-2013-3
Publication status	Published - 2019 Oct 1

Bibliographical note

Funding Information:
Authors are thankful to Department of Science & Technology, India (DST/INSPIRE Fellowship/2011/164), for financial support. Presently, Dr Samanta joined Incheon National University as researcher. Authors are grateful to reviewers for improving the paper.

Publisher Copyright:
© 2018, Islamic Azad University (IAU).

Keywords

Excel Mera 71
Genotoxicity
Haematology
Hepato-somatic index
Total nuclear abnormalities

ASJC Scopus subject areas

Environmental Engineering
Environmental Chemistry
General Agricultural and Biological Sciences

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10.1007/s13762-018-2013-3

Cite this

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title = "Assessment of adverse impacts of glyphosate-based herbicide, Excel Mera 71 by integrating multi-level biomarker responses in fishes",

abstract = "This work was aimed to investigate the adverse impacts of Excel Mera 71 on Anabas testudineus, Heteropneustes fossilis and Oreochromis niloticus under laboratory (17.2 mg/L) and field (750 g/acre) conditions based on multiple-level integrated biomarker responses. Haematological parameters were influenced significantly and showed species specificity after Excel Mera 71 exposure under both the conditions. Physiological indices (hepato-somatic index and condition factor) showed higher values; however, hepato-somatic index induced significantly under both the conditions (p < 0.05). Total nuclear abnormalities at molecular level revealed enhanced level. Responses were more adverse in laboratory (O. niloticus > H. fossilis > A. testudineus), while total nuclear abnormalities under field showed the order as: H. fossilis (0.49 ± 0.08) > A. testudineus (0.46 ± 0.10) > O. niloticus (0.27 ± 0.05). Moreover, multi-level integrated biomarker responses displayed responses as: O. niloticus (6.97 fold) > H. fossilis (4.01 fold) > A. testudineus (2.33 fold) in laboratory; however, under field condition, responses were totally different [A. testudineus–H. fossilis (3.98 fold) > O. niloticus (3.01 fold)]. Additionally, glyphosate concentration was significantly correlated with several multi-level biomarker responses (p < 0.05). Moreover, multi-level integrated biomarker responses clearly indicated the higher impacts under laboratory experiment. Present investigation documented that multi-level integrative biomarker responses should be considered as reliable tool for assessment of herbicidal intoxication.",

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note = "Funding Information: Authors are thankful to Department of Science & Technology, India (DST/INSPIRE Fellowship/2011/164), for financial support. Presently, Dr Samanta joined Incheon National University as researcher. Authors are grateful to reviewers for improving the paper. Publisher Copyright: {\textcopyright} 2018, Islamic Azad University (IAU).",

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AU - Jung, J.

AU - Ghosh, A. R.

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Assessment of adverse impacts of glyphosate-based herbicide, Excel Mera 71 by integrating multi-level biomarker responses in fishes

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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