Assessment of adverse impacts of glyphosate-based herbicide, Excel Mera 71 by integrating multi-level biomarker responses in fishes

P. Samanta, S. Pal, A. K. Mukherjee, T. Senapati, J. Jung, A. R. Ghosh

    Research output: Contribution to journalArticlepeer-review

    10 Citations (Scopus)

    Abstract

    This work was aimed to investigate the adverse impacts of Excel Mera 71 on Anabas testudineus, Heteropneustes fossilis and Oreochromis niloticus under laboratory (17.2 mg/L) and field (750 g/acre) conditions based on multiple-level integrated biomarker responses. Haematological parameters were influenced significantly and showed species specificity after Excel Mera 71 exposure under both the conditions. Physiological indices (hepato-somatic index and condition factor) showed higher values; however, hepato-somatic index induced significantly under both the conditions (p < 0.05). Total nuclear abnormalities at molecular level revealed enhanced level. Responses were more adverse in laboratory (O. niloticus > H. fossilis > A. testudineus), while total nuclear abnormalities under field showed the order as: H. fossilis (0.49 ± 0.08) > A. testudineus (0.46 ± 0.10) > O. niloticus (0.27 ± 0.05). Moreover, multi-level integrated biomarker responses displayed responses as: O. niloticus (6.97 fold) > H. fossilis (4.01 fold) > A. testudineus (2.33 fold) in laboratory; however, under field condition, responses were totally different [A. testudineus–H. fossilis (3.98 fold) > O. niloticus (3.01 fold)]. Additionally, glyphosate concentration was significantly correlated with several multi-level biomarker responses (p < 0.05). Moreover, multi-level integrated biomarker responses clearly indicated the higher impacts under laboratory experiment. Present investigation documented that multi-level integrative biomarker responses should be considered as reliable tool for assessment of herbicidal intoxication.

    Original languageEnglish
    Pages (from-to)6291-6300
    Number of pages10
    JournalInternational Journal of Environmental Science and Technology
    Volume16
    Issue number10
    DOIs
    Publication statusPublished - 2019 Oct 1

    Bibliographical note

    Funding Information:
    Authors are thankful to Department of Science & Technology, India (DST/INSPIRE Fellowship/2011/164), for financial support. Presently, Dr Samanta joined Incheon National University as researcher. Authors are grateful to reviewers for improving the paper.

    Publisher Copyright:
    © 2018, Islamic Azad University (IAU).

    Keywords

    • Excel Mera 71
    • Genotoxicity
    • Haematology
    • Hepato-somatic index
    • Total nuclear abnormalities

    ASJC Scopus subject areas

    • Environmental Engineering
    • Environmental Chemistry
    • General Agricultural and Biological Sciences

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