Abstract
We identified a potential molecular marker associated with meat quality traits in the myosin heavy chain 4, MYH4 gene of Landrace pigs. Sequencing revealed a single nucleotide polymorphism (SNP; g.-1398G>T) in the 5' upstream region of MYH4. It was significantly associated with the number of type IIa muscle fibers and water-holding capacity based on filter-paper fluid uptake. The GG genotype groups had a greater number of type IIa fibers and a larger area composed of type IIa fibers than the other genotype group (P = 0.004 and P = 0.061, respectively). Expression level of MYH4 gene in the genotype TT or GT was higher than in genotype of GG (P < 0.0001). The T allele may enhance expression level of MYH4 gene and then the portion of IIb type fiber in the muscle be increased by the T allelle. Therefore, we suggest that the g.-1398G>T in the 5' upstream region of the porcine MYH4 may be used as a molecular marker for meat quality traits, although its functional effect is not defined yet.
Original language | English |
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Pages (from-to) | 330-335 |
Number of pages | 6 |
Journal | Animal Science Journal |
Volume | 87 |
Issue number | 3 |
DOIs | |
Publication status | Published - 2016 Mar 1 |
Bibliographical note
Publisher Copyright:© 2016 Japanese Society of Animal Science.
Keywords
- Meat quality
- Muscle fiber composition
- Myosin heavy chain 4 gene
- Pig
- Single nucleotide polymorphism
ASJC Scopus subject areas
- General Medicine