Association of melanocortin 4 receptor (MC4R) and high mobility group AT-hook 1 (HMGA1) polymorphisms with pig growth and fat deposition traits

K. S. Kim; J. J. Lee; H. Y. Shin; B. H. Choi; C. K. Lee; J. J. Kim; B. W. Cho; T. H. Kim

doi:10.1111/j.1365-2052.2006.01482.x

Association of melanocortin 4 receptor (MC4R) and high mobility group AT-hook 1 (HMGA1) polymorphisms with pig growth and fat deposition traits

K. S. Kim, J. J. Lee, H. Y. Shin, B. H. Choi, C. K. Lee, J. J. Kim, B. W. Cho, T. H. Kim

Department of Biotechnology

Research output: Contribution to journal › Article › peer-review

51 Citations (Scopus)

Abstract

The aim of this study was to analyse the combined effect of melanocortin 4 receptor (MC4R) and high mobility group AT-hook 1 (HMGA1) polymorphisms on growth and fatness traits in Duroc pigs. No significant interaction was observed between MC4R and HMGA1 for back-fat traits. An additive mode of inheritance of both gene effects was found for average daily gain and lean meat content. Maximum mean differences from combined genotypic effects were over 2 mm for back fat, 70 g/day for average daily gain and 2% for lean meat content. Therefore, utilization of polymorphisms in both MC4R and HMGA1 for marker-assisted selection could result in an economic benefit to the pig industry.

Original language	English
Pages (from-to)	419-421
Number of pages	3
Journal	Animal Genetics
Volume	37
Issue number	4
DOIs	https://doi.org/10.1111/j.1365-2052.2006.01482.x
Publication status	Published - 2006 Aug

Keywords

Economic traits
HMGA1
MC4R
Pig breeding

ASJC Scopus subject areas

Animal Science and Zoology
Genetics

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10.1111/j.1365-2052.2006.01482.x

Cite this

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title = "Association of melanocortin 4 receptor (MC4R) and high mobility group AT-hook 1 (HMGA1) polymorphisms with pig growth and fat deposition traits",

abstract = "The aim of this study was to analyse the combined effect of melanocortin 4 receptor (MC4R) and high mobility group AT-hook 1 (HMGA1) polymorphisms on growth and fatness traits in Duroc pigs. No significant interaction was observed between MC4R and HMGA1 for back-fat traits. An additive mode of inheritance of both gene effects was found for average daily gain and lean meat content. Maximum mean differences from combined genotypic effects were over 2 mm for back fat, 70 g/day for average daily gain and 2% for lean meat content. Therefore, utilization of polymorphisms in both MC4R and HMGA1 for marker-assisted selection could result in an economic benefit to the pig industry.",

keywords = "Economic traits, HMGA1, MC4R, Pig breeding",

author = "Kim, {K. S.} and Lee, {J. J.} and Shin, {H. Y.} and Choi, {B. H.} and Lee, {C. K.} and Kim, {J. J.} and Cho, {B. W.} and Kim, {T. H.}",

year = "2006",

month = aug,

doi = "10.1111/j.1365-2052.2006.01482.x",

language = "English",

volume = "37",

pages = "419--421",

journal = "Animal Genetics",

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AU - Kim, K. S.

AU - Lee, J. J.

AU - Shin, H. Y.

AU - Choi, B. H.

AU - Lee, C. K.

AU - Kim, J. J.

AU - Cho, B. W.

AU - Kim, T. H.

PY - 2006/8

Y1 - 2006/8

N2 - The aim of this study was to analyse the combined effect of melanocortin 4 receptor (MC4R) and high mobility group AT-hook 1 (HMGA1) polymorphisms on growth and fatness traits in Duroc pigs. No significant interaction was observed between MC4R and HMGA1 for back-fat traits. An additive mode of inheritance of both gene effects was found for average daily gain and lean meat content. Maximum mean differences from combined genotypic effects were over 2 mm for back fat, 70 g/day for average daily gain and 2% for lean meat content. Therefore, utilization of polymorphisms in both MC4R and HMGA1 for marker-assisted selection could result in an economic benefit to the pig industry.

AB - The aim of this study was to analyse the combined effect of melanocortin 4 receptor (MC4R) and high mobility group AT-hook 1 (HMGA1) polymorphisms on growth and fatness traits in Duroc pigs. No significant interaction was observed between MC4R and HMGA1 for back-fat traits. An additive mode of inheritance of both gene effects was found for average daily gain and lean meat content. Maximum mean differences from combined genotypic effects were over 2 mm for back fat, 70 g/day for average daily gain and 2% for lean meat content. Therefore, utilization of polymorphisms in both MC4R and HMGA1 for marker-assisted selection could result in an economic benefit to the pig industry.

KW - Economic traits

KW - HMGA1

KW - MC4R

KW - Pig breeding

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U2 - 10.1111/j.1365-2052.2006.01482.x

DO - 10.1111/j.1365-2052.2006.01482.x

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AN - SCOPUS:33746216963

SN - 0268-9146

VL - 37

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JO - Animal Genetics

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Association of melanocortin 4 receptor (MC4R) and high mobility group AT-hook 1 (HMGA1) polymorphisms with pig growth and fat deposition traits

Abstract

Keywords

ASJC Scopus subject areas

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