Asthma-like symptoms are increased in the metabolic syndrome

Eun Joo Lee; Kwang Ho In; Eun Sil Ha; Kyung Ju Lee; Gyu Young Hur; Eun Hae Kang; Ki Hwan Jung; Sung Yong Lee; Je Hyeong Kim; Sang Yeub Lee; Chol Shin; Jae Jeong Shim; Kyung Ho Kang; Se Hwa Yoo

doi:10.1080/02770900802660931

Asthma-like symptoms are increased in the metabolic syndrome

Eun Joo Lee, Kwang Ho In, Eun Sil Ha, Kyung Ju Lee, Gyu Young Hur, Eun Hae Kang, Ki Hwan Jung, Sung Yong Lee, Je Hyeong Kim, Sang Yeub Lee, Chol Shin, Jae Jeong Shim, Kyung Ho Kang, Se Hwa Yoo

Research output: Contribution to journal › Article › peer-review

56 Citations (Scopus)

Abstract

Background. The prevalence of obesity and asthma has been increasing during the last several decades. Obesity has been reported to be associated with asthma. Obesity, especially abdominal obesity, is the main component of the metabolic syndrome. Objectives. We thus hypothesized that metabolic syndrome is an important contributing factor for the development of asthma-like symptoms. Methods. The Korean Health and Genome Study started in 2001 as an ongoing population-based study of Korean adults 40 to 69 years of age. The prevalence of asthma-like symptoms in the previous 12 months was obtained by a questionnaire, and spirometric testing was conducted. Results. Among the 10,038 participants, the data from 9,942 individuals (4,716 men and 5,226 women) was available. Asthma-like symptoms (wheeze [p = 0.0006], resting dyspnea [p = 0.0062], and post-exercise dyspnea [p 0.0001]) were increased in the subjects of the metabolic syndrome group. Subjects with asthma-like symptoms had a decreased lung function compared to subjects without asthma-like symptoms. Among the components of the metabolic syndrome, abdominal obesity and hypertension were the risk factors for asthma-like symptoms. Conclusions. Metabolic syndrome is associated with asthma-like symptoms. Among the components of metabolic syndrome, abdominal obesity and hypertension are the risk factors for asthma-like symptoms.

Original language	English
Pages (from-to)	339-342
Number of pages	4
Journal	Journal of Asthma
Volume	46
Issue number	4
DOIs	https://doi.org/10.1080/02770900802660931
Publication status	Published - 2009 May

Bibliographical note

Funding Information:
Supported by the National Genome Research Institute, National Institutes of Health, Korea (budgets 2001-347-6111-221 and 2002-347-6111-221).

Funding Information:
C.S. received research funding from the National Genome Research Institute, National Institutes of Health, Korea.

Keywords

Asthma-like symptoms
Epidemiology
Korea
Metabolic syndrome

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Immunology and Allergy
Pulmonary and Respiratory Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1080/02770900802660931

Cite this

@article{43bdb403baad49a0a3cbe4e73fbee900,

title = "Asthma-like symptoms are increased in the metabolic syndrome",

abstract = "Background. The prevalence of obesity and asthma has been increasing during the last several decades. Obesity has been reported to be associated with asthma. Obesity, especially abdominal obesity, is the main component of the metabolic syndrome. Objectives. We thus hypothesized that metabolic syndrome is an important contributing factor for the development of asthma-like symptoms. Methods. The Korean Health and Genome Study started in 2001 as an ongoing population-based study of Korean adults 40 to 69 years of age. The prevalence of asthma-like symptoms in the previous 12 months was obtained by a questionnaire, and spirometric testing was conducted. Results. Among the 10,038 participants, the data from 9,942 individuals (4,716 men and 5,226 women) was available. Asthma-like symptoms (wheeze [p = 0.0006], resting dyspnea [p = 0.0062], and post-exercise dyspnea [p 0.0001]) were increased in the subjects of the metabolic syndrome group. Subjects with asthma-like symptoms had a decreased lung function compared to subjects without asthma-like symptoms. Among the components of the metabolic syndrome, abdominal obesity and hypertension were the risk factors for asthma-like symptoms. Conclusions. Metabolic syndrome is associated with asthma-like symptoms. Among the components of metabolic syndrome, abdominal obesity and hypertension are the risk factors for asthma-like symptoms.",

keywords = "Asthma-like symptoms, Epidemiology, Korea, Metabolic syndrome",

author = "Lee, {Eun Joo} and In, {Kwang Ho} and Ha, {Eun Sil} and Lee, {Kyung Ju} and Hur, {Gyu Young} and Kang, {Eun Hae} and Jung, {Ki Hwan} and Lee, {Sung Yong} and Kim, {Je Hyeong} and Lee, {Sang Yeub} and Chol Shin and Shim, {Jae Jeong} and Kang, {Kyung Ho} and Yoo, {Se Hwa}",

note = "Funding Information: Supported by the National Genome Research Institute, National Institutes of Health, Korea (budgets 2001-347-6111-221 and 2002-347-6111-221). Funding Information: C.S. received research funding from the National Genome Research Institute, National Institutes of Health, Korea.",

year = "2009",

month = may,

doi = "10.1080/02770900802660931",

language = "English",

volume = "46",

pages = "339--342",

journal = "Journal of Asthma",

issn = "0277-0903",

publisher = "Taylor & Francis Group LLC Philadelphia",

number = "4",

}

TY - JOUR

T1 - Asthma-like symptoms are increased in the metabolic syndrome

AU - Lee, Eun Joo

AU - In, Kwang Ho

AU - Ha, Eun Sil

AU - Lee, Kyung Ju

AU - Hur, Gyu Young

AU - Kang, Eun Hae

AU - Jung, Ki Hwan

AU - Lee, Sung Yong

AU - Kim, Je Hyeong

AU - Lee, Sang Yeub

AU - Shin, Chol

AU - Shim, Jae Jeong

AU - Kang, Kyung Ho

AU - Yoo, Se Hwa

N1 - Funding Information: Supported by the National Genome Research Institute, National Institutes of Health, Korea (budgets 2001-347-6111-221 and 2002-347-6111-221). Funding Information: C.S. received research funding from the National Genome Research Institute, National Institutes of Health, Korea.

PY - 2009/5

Y1 - 2009/5

N2 - Background. The prevalence of obesity and asthma has been increasing during the last several decades. Obesity has been reported to be associated with asthma. Obesity, especially abdominal obesity, is the main component of the metabolic syndrome. Objectives. We thus hypothesized that metabolic syndrome is an important contributing factor for the development of asthma-like symptoms. Methods. The Korean Health and Genome Study started in 2001 as an ongoing population-based study of Korean adults 40 to 69 years of age. The prevalence of asthma-like symptoms in the previous 12 months was obtained by a questionnaire, and spirometric testing was conducted. Results. Among the 10,038 participants, the data from 9,942 individuals (4,716 men and 5,226 women) was available. Asthma-like symptoms (wheeze [p = 0.0006], resting dyspnea [p = 0.0062], and post-exercise dyspnea [p 0.0001]) were increased in the subjects of the metabolic syndrome group. Subjects with asthma-like symptoms had a decreased lung function compared to subjects without asthma-like symptoms. Among the components of the metabolic syndrome, abdominal obesity and hypertension were the risk factors for asthma-like symptoms. Conclusions. Metabolic syndrome is associated with asthma-like symptoms. Among the components of metabolic syndrome, abdominal obesity and hypertension are the risk factors for asthma-like symptoms.

AB - Background. The prevalence of obesity and asthma has been increasing during the last several decades. Obesity has been reported to be associated with asthma. Obesity, especially abdominal obesity, is the main component of the metabolic syndrome. Objectives. We thus hypothesized that metabolic syndrome is an important contributing factor for the development of asthma-like symptoms. Methods. The Korean Health and Genome Study started in 2001 as an ongoing population-based study of Korean adults 40 to 69 years of age. The prevalence of asthma-like symptoms in the previous 12 months was obtained by a questionnaire, and spirometric testing was conducted. Results. Among the 10,038 participants, the data from 9,942 individuals (4,716 men and 5,226 women) was available. Asthma-like symptoms (wheeze [p = 0.0006], resting dyspnea [p = 0.0062], and post-exercise dyspnea [p 0.0001]) were increased in the subjects of the metabolic syndrome group. Subjects with asthma-like symptoms had a decreased lung function compared to subjects without asthma-like symptoms. Among the components of the metabolic syndrome, abdominal obesity and hypertension were the risk factors for asthma-like symptoms. Conclusions. Metabolic syndrome is associated with asthma-like symptoms. Among the components of metabolic syndrome, abdominal obesity and hypertension are the risk factors for asthma-like symptoms.

KW - Asthma-like symptoms

KW - Epidemiology

KW - Korea

KW - Metabolic syndrome

UR - http://www.scopus.com/inward/record.url?scp=67649830897&partnerID=8YFLogxK

U2 - 10.1080/02770900802660931

DO - 10.1080/02770900802660931

M3 - Article

C2 - 19484665

AN - SCOPUS:67649830897

SN - 0277-0903

VL - 46

SP - 339

EP - 342

JO - Journal of Asthma

JF - Journal of Asthma

IS - 4

ER -

Asthma-like symptoms are increased in the metabolic syndrome

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this