Atlas construction via dictionary learning and group sparsity

Feng Shi, Li Wang, Guorong Wu, Yu Zhang, Manhua Liu, John H. Gilmore, Weili Lin, Dinggang Shen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Citations (Scopus)


Atlas construction generally includes first an image registration step to normalize all images into a common space and then an atlas building step to fuse all the aligned images. Although numerous atlas construction studies have been performed to improve the accuracy of image registration step, simple averaging or weighted averaging is often used for the atlas building step. In this paper, we propose a novel patch-based sparse representation method for atlas construction, especially for the atlas building step. By taking advantage of local sparse representation, more distinct anatomical details can be revealed in the built atlas. Also, together with the constraint on group structure of representations and the use of overlapping patches, anatomical consistency between neighboring patches can be ensured. The proposed method has been applied to 73 neonatal MR images with poor spatial resolution and low tissue contrast, for building unbiased neonatal brain atlas. Experimental results demonstrate that the proposed method can enhance the quality of built atlas by discovering more anatomical details especially in cortical regions, and perform better in a neonatal data normalization application, compared to other existing start-of-the-art nonlinear neonatal brain atlases.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer-Assisted Intervention, MICCAI2012 - 15th International Conference, Proceedings
EditorsNicholas Ayache, Herve Delingette, Polina Golland, Kensaku Mori
PublisherSpringer Verlag
Number of pages9
ISBN (Print)9783642334146
Publication statusPublished - 2012
Externally publishedYes
Event15th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2012 - Nice, France
Duration: 2012 Oct 12012 Oct 5

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume7510 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349


Conference15th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2012

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)


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