Automatic Detection of Craniomaxillofacial Anatomical Landmarks on CBCT Images Using 3D Mask R-CNN

Yankun Lang; Li Wang; Pew Thian Yap; Chunfeng Lian; Hannah Deng; Kim Han Thung; Deqiang Xiao; Peng Yuan; Steve G.F. Shen; Jaime Gateno; Tianshu Kuang; David M. Alfi; James J. Xia; Dinggang Shen

doi:10.1007/978-3-030-35817-4_16

Automatic Detection of Craniomaxillofacial Anatomical Landmarks on CBCT Images Using 3D Mask R-CNN

Yankun Lang, Li Wang, Pew Thian Yap, Chunfeng Lian, Hannah Deng, Kim Han Thung, Deqiang Xiao, Peng Yuan, Steve G.F. Shen, Jaime Gateno, Tianshu Kuang, David M. Alfi, James J. Xia, Dinggang Shen

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

7 Citations (Scopus)

Abstract

Craniomaxillofacial (CMF) landmark localization is an important step for characterizing jaw deformities and designing surgical plans. However, due to the complexity of facial structure and the deformities of CMF patients, it is still difficult to accurately localize a large scale of landmarks simultaneously. In this work, we propose a three-stage coarse-to-fine deep learning method for digitizing 105 anatomical craniomaxillofacial landmarks on cone-beam computed tomography (CBCT) images. The first stage outputs a coarse location of each landmark from a low-resolution image, which is gradually refined in the next two stages using the corresponding higher resolution images. Our method is implemented using Mask R-CNN, by also incorporating a new loss function that learns the geometrical relationships between the landmarks in the form of a root/leaf structure. We evaluate our approach on 49 CBCT scans of patients and achieve an average detection error of 1.75 ± 0.91 mm. Experimental results show that our approach overperforms the related methods in the term of accuracy.

Original language	English
Title of host publication	Graph Learning in Medical Imaging - 1st International Workshop, GLMI 2019, held in Conjunction with MICCAI 2019, Proceedings
Editors	Daoqiang Zhang, Luping Zhou, Biao Jie, Mingxia Liu
Publisher	Springer
Pages	130-137
Number of pages	8
ISBN (Print)	9783030358167
DOIs	https://doi.org/10.1007/978-3-030-35817-4_16
Publication status	Published - 2019
Event	1st International Workshop on Graph Learning in Medical Imaging, GLMI 2019 held in conjunction with the 22nd International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2019 - Shenzhen, China Duration: 2019 Oct 17 → 2019 Oct 17

Publication series

Name	Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume	11849 LNCS
ISSN (Print)	0302-9743
ISSN (Electronic)	1611-3349

Conference

Conference	1st International Workshop on Graph Learning in Medical Imaging, GLMI 2019 held in conjunction with the 22nd International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2019
Country/Territory	China
City	Shenzhen
Period	19/10/17 → 19/10/17

Bibliographical note

Publisher Copyright:
© 2019, Springer Nature Switzerland AG.

ASJC Scopus subject areas

Theoretical Computer Science
General Computer Science

Access to Document

10.1007/978-3-030-35817-4_16

Cite this

Lang, Y., Wang, L., Yap, P. T., Lian, C., Deng, H., Thung, K. H., Xiao, D., Yuan, P., Shen, S. G. F., Gateno, J., Kuang, T., Alfi, D. M., Xia, J. J., & Shen, D. (2019). Automatic Detection of Craniomaxillofacial Anatomical Landmarks on CBCT Images Using 3D Mask R-CNN. In D. Zhang, L. Zhou, B. Jie, & M. Liu (Eds.), Graph Learning in Medical Imaging - 1st International Workshop, GLMI 2019, held in Conjunction with MICCAI 2019, Proceedings (pp. 130-137). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 11849 LNCS). Springer. https://doi.org/10.1007/978-3-030-35817-4_16

Automatic Detection of Craniomaxillofacial Anatomical Landmarks on CBCT Images Using 3D Mask R-CNN. / Lang, Yankun; Wang, Li; Yap, Pew Thian et al.
Graph Learning in Medical Imaging - 1st International Workshop, GLMI 2019, held in Conjunction with MICCAI 2019, Proceedings. ed. / Daoqiang Zhang; Luping Zhou; Biao Jie; Mingxia Liu. Springer, 2019. p. 130-137 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 11849 LNCS).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Lang, Y, Wang, L, Yap, PT, Lian, C, Deng, H, Thung, KH, Xiao, D, Yuan, P, Shen, SGF, Gateno, J, Kuang, T, Alfi, DM, Xia, JJ & Shen, D 2019, Automatic Detection of Craniomaxillofacial Anatomical Landmarks on CBCT Images Using 3D Mask R-CNN. in D Zhang, L Zhou, B Jie & M Liu (eds), Graph Learning in Medical Imaging - 1st International Workshop, GLMI 2019, held in Conjunction with MICCAI 2019, Proceedings. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 11849 LNCS, Springer, pp. 130-137, 1st International Workshop on Graph Learning in Medical Imaging, GLMI 2019 held in conjunction with the 22nd International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2019, Shenzhen, China, 19/10/17. https://doi.org/10.1007/978-3-030-35817-4_16

Lang Y, Wang L, Yap PT, Lian C, Deng H, Thung KH et al. Automatic Detection of Craniomaxillofacial Anatomical Landmarks on CBCT Images Using 3D Mask R-CNN. In Zhang D, Zhou L, Jie B, Liu M, editors, Graph Learning in Medical Imaging - 1st International Workshop, GLMI 2019, held in Conjunction with MICCAI 2019, Proceedings. Springer. 2019. p. 130-137. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)). doi: 10.1007/978-3-030-35817-4_16

Lang, Yankun ; Wang, Li ; Yap, Pew Thian et al. / Automatic Detection of Craniomaxillofacial Anatomical Landmarks on CBCT Images Using 3D Mask R-CNN. Graph Learning in Medical Imaging - 1st International Workshop, GLMI 2019, held in Conjunction with MICCAI 2019, Proceedings. editor / Daoqiang Zhang ; Luping Zhou ; Biao Jie ; Mingxia Liu. Springer, 2019. pp. 130-137 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)).

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title = "Automatic Detection of Craniomaxillofacial Anatomical Landmarks on CBCT Images Using 3D Mask R-CNN",

abstract = "Craniomaxillofacial (CMF) landmark localization is an important step for characterizing jaw deformities and designing surgical plans. However, due to the complexity of facial structure and the deformities of CMF patients, it is still difficult to accurately localize a large scale of landmarks simultaneously. In this work, we propose a three-stage coarse-to-fine deep learning method for digitizing 105 anatomical craniomaxillofacial landmarks on cone-beam computed tomography (CBCT) images. The first stage outputs a coarse location of each landmark from a low-resolution image, which is gradually refined in the next two stages using the corresponding higher resolution images. Our method is implemented using Mask R-CNN, by also incorporating a new loss function that learns the geometrical relationships between the landmarks in the form of a root/leaf structure. We evaluate our approach on 49 CBCT scans of patients and achieve an average detection error of 1.75 ± 0.91 mm. Experimental results show that our approach overperforms the related methods in the term of accuracy.",

author = "Yankun Lang and Li Wang and Yap, {Pew Thian} and Chunfeng Lian and Hannah Deng and Thung, {Kim Han} and Deqiang Xiao and Peng Yuan and Shen, {Steve G.F.} and Jaime Gateno and Tianshu Kuang and Alfi, {David M.} and Xia, {James J.} and Dinggang Shen",

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AU - Deng, Hannah

AU - Thung, Kim Han

AU - Xiao, Deqiang

AU - Yuan, Peng

AU - Shen, Steve G.F.

AU - Gateno, Jaime

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AU - Alfi, David M.

AU - Xia, James J.

AU - Shen, Dinggang

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N2 - Craniomaxillofacial (CMF) landmark localization is an important step for characterizing jaw deformities and designing surgical plans. However, due to the complexity of facial structure and the deformities of CMF patients, it is still difficult to accurately localize a large scale of landmarks simultaneously. In this work, we propose a three-stage coarse-to-fine deep learning method for digitizing 105 anatomical craniomaxillofacial landmarks on cone-beam computed tomography (CBCT) images. The first stage outputs a coarse location of each landmark from a low-resolution image, which is gradually refined in the next two stages using the corresponding higher resolution images. Our method is implemented using Mask R-CNN, by also incorporating a new loss function that learns the geometrical relationships between the landmarks in the form of a root/leaf structure. We evaluate our approach on 49 CBCT scans of patients and achieve an average detection error of 1.75 ± 0.91 mm. Experimental results show that our approach overperforms the related methods in the term of accuracy.

AB - Craniomaxillofacial (CMF) landmark localization is an important step for characterizing jaw deformities and designing surgical plans. However, due to the complexity of facial structure and the deformities of CMF patients, it is still difficult to accurately localize a large scale of landmarks simultaneously. In this work, we propose a three-stage coarse-to-fine deep learning method for digitizing 105 anatomical craniomaxillofacial landmarks on cone-beam computed tomography (CBCT) images. The first stage outputs a coarse location of each landmark from a low-resolution image, which is gradually refined in the next two stages using the corresponding higher resolution images. Our method is implemented using Mask R-CNN, by also incorporating a new loss function that learns the geometrical relationships between the landmarks in the form of a root/leaf structure. We evaluate our approach on 49 CBCT scans of patients and achieve an average detection error of 1.75 ± 0.91 mm. Experimental results show that our approach overperforms the related methods in the term of accuracy.

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Automatic Detection of Craniomaxillofacial Anatomical Landmarks on CBCT Images Using 3D Mask R-CNN

Abstract

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