Objectives: To characterise the behavioural and neuropsychiatric disturbances of patients with three clinical subtypes of frontotemporal dementia (FTD): behavioural variant FTD (bvFTD), semantic dementia (SD) and progressive non-fluent aphasia (PNFA). Methods: Consecutive series of 66 patients with bvFTD, 58 patients with SD and 21 patients with PNFA were compared using the Frontal Behavioural Inventory (FBI) and the Neuropsychiatric Inventory (NPI). Results: Patients with bvFTD had more behavioural and neuropsychiatric disturbances than patients with PNFA based on the total scores of FBI and NPI. When comparing subtotal and item scores of FBI and NPI, there were some significant differences among three clinical subtypes of FTD. Conclusion: There are some distinct patterns of behavioural and neuropsychiatric disturbance among three clinical subtypes of FTD.
Bibliographical noteFunding Information:
This study was supported mainly by grants of the Korea Healthcare Technology R&D Project, Ministry of Health and Welfare, Republic of Korea (HI12C0135), and the Original Technology Research Program for Brain Science through the National Research Foundation of Korea (NRF) funded by the Korean Government (MSIP) (No. 2014M3C7A1064752) and partially by a grant of Korea University. The authors declare no conflicts of interest.
© 2017 AJA Inc.
- behavioural symptoms
- brief psychiatric rating scale
- frontotemporal dementia
ASJC Scopus subject areas
- Community and Home Care
- Geriatrics and Gerontology