Bifenthrin impairs the functions of Leydig and Sertoli cells in mice via mitochondrion-endoplasmic reticulum dysregulation

Jiyeon Ham, Seungkwon You, Whasun Lim, Gwonhwa Song

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

Bifenthrin induces testicular cell death by suppressing the cell cycle and stimulating ER stress and mitochondrial apoptosis-related proteins in mice.

Original languageEnglish
Article number115174
JournalEnvironmental Pollution
Volume266
DOIs
Publication statusPublished - 2020 Nov

Bibliographical note

Funding Information:
This article was supported a grant that is National Research Foundation of Korea (NRF) grant funded by the Ministry of Science and ICT(MIST) in South Korea (grant number: 2018R1C1B6009048 ).

Publisher Copyright:
© 2020 Elsevier Ltd

Keywords

  • Apoptosis
  • Bifenthrin
  • Leydig and Sertoli cells
  • MAPK/PI3K pathway
  • Steroidogenesis
  • Testis dysfunction

ASJC Scopus subject areas

  • Toxicology
  • Pollution
  • Health, Toxicology and Mutagenesis

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