Bilateral xanthogranuloma of the breast: Radiologic findings and pathologic correlation

Sung Ho Hwang, Eun Ju Son, Ki Keun Oh, Eun Kyung Kim, Joon Jung, Woo Hee Jung

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


A xanthogranuloma (XG) is a rare benign histiocytic disorder that occurs mostly in infants and young children. Approximately 15% of XGs occur in adults and usually appear as solitary lesions in the head and the neck region. In most cases, an XG appears as a solitary yellow-red cutaneous nodule in the head and the neck region that regresses spontaneously over a course of months to years. An extracutaneous XG is uncommon, and it can occur with or without a cutaneous XG. An extracutaneous XG most commonly occurs in the eye, but findings at other sites such as the central nervous system, lungs, liver, spleen, kidneys, and bone have also been reported. The pathogenesis of XGs is unknown. Although physical and infectious factors have been considered, most investigators postulate that they are caused by a reactive response to an unknown stimulus. Xanthogranulomas can be divided into juvenile and adult forms. Distinctive from the juvenile form, the adult XG rarely undergoes a spontaneous regression, and concomitant extracutaneous examples are very uncommon. Patients with adult XGs are mostly in their late teens to late 30s, although approximately 5% of the patients are in their 60s to 70s. We report an exceptional case of an adult breast XG in a 60-year-old woman.

Original languageEnglish
Pages (from-to)535-537
Number of pages3
JournalJournal of Ultrasound in Medicine
Issue number4
Publication statusPublished - 2007 Apr

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging


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