Bio-psycho-social risk factors for depression

Sang Won Jeon, Meysam Amidfar, Yong Ku Kim

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)


Major depressive disorder (MDD) is one of the most common psychiatric disorders. In general, 10% to 25% of women and 5% to 10% of men are at risk for having MDD once in their lifetime. In addition, 5% to 10% of the population suffers from MDD, while 3% to 5% of the population is estimated to have severe MDD that requires treatment [1]. According to the Global Burden of Disease (published by the World Health Organization), which considers both mortality and morbidity, MDD ranked fourth place among all diseases. It is expected to rise to second place by 2020 following ischemic heart disease [2]. The most effective way to reduce the burden of MDD is to prevent its onset by first identifying high-risk individuals rather than treating MDD that has already started. MDD prevention includes efforts to remove or reduce MDD risk factors. However, MDD is thought to have multidimensional causes and pathogenesis in terms of bio-psycho-social variables, thus risk factors are complicated. In this paper, the bio-psycho-social risk factors for MDD are summarized.

Original languageEnglish
Title of host publicationMajor Depressive Disorder
Subtitle of host publicationRisk Factors, Characteristics and Treatment Options
PublisherNova Science Publishers, Inc.
Number of pages20
ISBN (Electronic)9781536120035
ISBN (Print)9781536119800
Publication statusPublished - 2017 Jan 1
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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