Bioactive compounds from the genus broussonetia

Dongho Lee; A. Douglas Kinghorn

doi:10.1016/S1572-5995(03)80137-0

Bioactive compounds from the genus broussonetia

Dongho Lee, A. Douglas Kinghorn

Research output: Chapter in Book/Report/Conference proceeding › Chapter

8 Citations (Scopus)

Abstract

The genus Broussonetia of the Moraceae (mulberry family) is of both ethnomedical and industrial interest. Of the approximately 30 species in this genus, only three have been subjected to previous phytochemical investigation, namely, B. kazinoki, B. papyrifera, and B. zeylanica. From over 100 compounds isolated from these species, the major secondary metabolites reported thus far are alkaloids of the pyrrolidine type and several types of flavonoids. Some of these compounds have exhibited various biological activities, such antioxidative, aromatase inhibitory, cytotoxic, glycosidase inhibitory, and platelet aggregation inhibitory effects. The biologically active constituents of the species in the genus Broussonetia are discussed in detail.

Original language	English
Title of host publication	Studies in Natural Products Chemistry
Publisher	Elsevier
Pages	3-33
Number of pages	31
Edition	PART I
DOIs	https://doi.org/10.1016/S1572-5995(03)80137-0
Publication status	Published - 2003
Externally published	Yes

Publication series

Name	Studies in Natural Products Chemistry
Number	PART I
Volume	28
ISSN (Print)	1572-5995

Bibliographical note

Funding Information:
The laboratory work on potential cancer chemopreventive agents carried out at the University of Illinois at Chicago was supported by program project P01 CA48112 (Principal Investigator, John M. Pezzuto, Ph.D.), funded by the National Cancer Institute, NIH, Bethesda, Maryland, U.S.A.

Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.

ASJC Scopus subject areas

Drug Discovery
Organic Chemistry

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10.1016/S1572-5995(03)80137-0

Cite this

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abstract = "The genus Broussonetia of the Moraceae (mulberry family) is of both ethnomedical and industrial interest. Of the approximately 30 species in this genus, only three have been subjected to previous phytochemical investigation, namely, B. kazinoki, B. papyrifera, and B. zeylanica. From over 100 compounds isolated from these species, the major secondary metabolites reported thus far are alkaloids of the pyrrolidine type and several types of flavonoids. Some of these compounds have exhibited various biological activities, such antioxidative, aromatase inhibitory, cytotoxic, glycosidase inhibitory, and platelet aggregation inhibitory effects. The biologically active constituents of the species in the genus Broussonetia are discussed in detail.",

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note = "Funding Information: The laboratory work on potential cancer chemopreventive agents carried out at the University of Illinois at Chicago was supported by program project P01 CA48112 (Principal Investigator, John M. Pezzuto, Ph.D.), funded by the National Cancer Institute, NIH, Bethesda, Maryland, U.S.A. Copyright: Copyright 2019 Elsevier B.V., All rights reserved.",

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Bioactive compounds from the genus broussonetia

Abstract

Publication series

Bibliographical note

ASJC Scopus subject areas

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