Bioinspired self-adhesive polymer for surface modification to improve antifouling property

Seong Beom Heo, Young Sil Jeon, Young Jun Kim, Soo Hyun Kim, Ji Heung Kim

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


The catechol functional group of dopamine (3,4-dihydroxyphenethylamine) forms a strong coordinate bond with both inorganic and organic substrates in a wet environment. The nonfouling surfaces required for this process are typically prepared through the immobilization of poly(ethylene glycol), so-called, PEGylation. In this work, polyaspartamides containing adhesive catechol and methoxy PEG pendants were synthesized from polysuccinimide through successive aminolysis reactions. The adhesion and crosslinking of the polyaspartamide derivatives in pH-controlled aqueous media was successfully utilized to modify a glass surface using a simple immersion method. Contact angle, α-step profiler, SEM and EDS, XPS, and AFM were used to characterize and verify the surface coating. In addition, the biocompatibility and antifouling properties of the modified surface were elucidated with a cell viability test, and a protein adsorption experiment, respectively. This biocompatible polymer system has biomedical application potential for use in adhesives and the surface coating of various biomaterials.

Original languageEnglish
Pages (from-to)811-819
Number of pages9
JournalJournal of Coatings Technology and Research
Issue number6
Publication statusPublished - 2013 Nov


  • Antifouling
  • Dopamine
  • PEG
  • Polyaspartamide
  • Surface modification

ASJC Scopus subject areas

  • Chemistry(all)
  • Surfaces and Interfaces
  • Surfaces, Coatings and Films
  • Colloid and Surface Chemistry


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