Biologically Safe, Degradable Self-Destruction System for On-Demand, Programmable Transient Electronics

Jeong Woong Shin, Jong Chan Choe, Joong Hoon Lee, Won Bae Han, Tae Min Jang, Gwan Jin Ko, Seung Min Yang, Yu Gyeong Kim, Jaesun Joo, Bong Hee Lim, Eunkyoung Park, Suk Won Hwang

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)


The lifetime of transient electronic components can be programmed via the use of encapsulation/passivation layers or of on-demand, stimuli-responsive polymers (heat, light, or chemicals), but yet most research is limited to slow dissolution rate, hazardous constituents, or byproducts, or complicated synthesis of reactants. Here we present a physicochemical destruction system with dissolvable, nontoxic materials as an efficient, multipurpose platform, where chemically produced bubbles rapidly collapse device structures and acidic molecules accelerate dissolution of functional traces. Extensive studies of composites based on biodegradable polymers (gelatin and poly(lactic-co-glycolic acid)) and harmless blowing agents (organic acid and bicarbonate salt) validate the capability for the desired system. Integration with wearable/recyclable electronic components, fast-degradable device layouts, and wireless microfluidic devices highlights potential applicability toward versatile/multifunctional transient systems. In vivo toxicity tests demonstrate biological safety of the proposed system.

Original languageEnglish
Pages (from-to)19310-19320
Number of pages11
JournalACS nano
Issue number12
Publication statusPublished - 2021 Dec 28

Bibliographical note

Funding Information:
This work was supported by Korea University, KU-KIST Graduate School of Converging Science and Technology Program, Korea Medical Device Development Fund Grant funded by the Korea government (the Ministry of Science and ICT, the Ministry of Trade, Industry & Energy, the Ministry of Health & Welfare, and the Ministry of Food and Drug Safety) (202012D30), and National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (grant NRF-2017R1E1A1A01075027). This research was supported by the MSIT(Ministry of Science and ICT), Korea, under the ICT Creative Consilience program (IITP-2021-2020-0-01819) supervised by the IITP (Institute for Information & communications Technology Planning & Evaluation).

Publisher Copyright:
© 2021 American Chemical Society.


  • biodegradable
  • biosafe
  • self-destruction
  • transient electronics
  • triggering

ASJC Scopus subject areas

  • General Materials Science
  • General Engineering
  • General Physics and Astronomy


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