Bioresorbable Silicon Nanomembranes and Iron Catalyst Nanoparticles for Flexible, Transient Electrochemical Dopamine Monitors

Hyun Seung Kim; Seung Min Yang; Tae Min Jang; Nuri Oh; Hee Soo Kim; Suk Won Hwang

doi:10.1002/adhm.201801071

Bioresorbable Silicon Nanomembranes and Iron Catalyst Nanoparticles for Flexible, Transient Electrochemical Dopamine Monitors

Hyun Seung Kim
, Seung Min Yang
, Tae Min Jang
, Nuri Oh
, Hee Soo Kim
, Suk Won Hwang^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

66 Citations (Scopus)

Abstract

A strategy of materials synthesis, characteristic evaluations, and manufacturing process for a mechanically elastic, biologically safe silicon-based dopamine detector that is designed to be completely transient, i.e., dissolved in water and/or biofluids, potentially in the brain after a desired period of operation, is introduced. Use of inexpensive, bioresorbable iron (Fe)-based nanoparticles (NPs) is one of the attractive choices for efficient catalytic oxidation of dopamine as an alternative for noble, nontransient platinum (Pt) nanoparticles, based on extensive studies of synthesized materials and catalytic reactions. Arrays of transient dopamine sensors validate electrochemical functionality to determine physiological levels of dopamine and to selectively sense dopamine in a variety of neurotransmitters, illuminating feasibilities for a higher level of soft, transient electronic implants integrated with other components of overall system.

Original language	English
Article number	1801071
Journal	Advanced Healthcare Materials
Volume	7
Issue number	24
DOIs	https://doi.org/10.1002/adhm.201801071
Publication status	Published - 2018 Dec 19

Bibliographical note

Funding Information:
H.-S.K. and S.M.Y. contributed equally to this work. This work was supported by KU-KIST Graduate School of Converging Science and Technology Program, KU Future Research Grant, the KIST project (2E27930), and Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of science, ICT & Future Planning (grant NRF-2017R1E1A1A01075027).

Publisher Copyright:
© 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Keywords

bioresorbable
dopamine sensors
flexible
iron catalyst
transient

ASJC Scopus subject areas

Biomaterials
Biomedical Engineering
Pharmaceutical Science

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10.1002/adhm.201801071

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abstract = "A strategy of materials synthesis, characteristic evaluations, and manufacturing process for a mechanically elastic, biologically safe silicon-based dopamine detector that is designed to be completely transient, i.e., dissolved in water and/or biofluids, potentially in the brain after a desired period of operation, is introduced. Use of inexpensive, bioresorbable iron (Fe)-based nanoparticles (NPs) is one of the attractive choices for efficient catalytic oxidation of dopamine as an alternative for noble, nontransient platinum (Pt) nanoparticles, based on extensive studies of synthesized materials and catalytic reactions. Arrays of transient dopamine sensors validate electrochemical functionality to determine physiological levels of dopamine and to selectively sense dopamine in a variety of neurotransmitters, illuminating feasibilities for a higher level of soft, transient electronic implants integrated with other components of overall system.",

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AU - Oh, Nuri

AU - Kim, Hee Soo

AU - Hwang, Suk Won

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Bioresorbable Silicon Nanomembranes and Iron Catalyst Nanoparticles for Flexible, Transient Electrochemical Dopamine Monitors

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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