Biosafe, Eco-Friendly Levan Polysaccharide toward Transient Electronics

Ki Yoon Kwon; Ju Seung Lee; Gwan Jin Ko; Sung Hyuk Sunwoo; Sori Lee; Young Jin Jo; Chul Hee Choi; Suk Won Hwang; Tae il Kim

doi:10.1002/smll.201801332

Biosafe, Eco-Friendly Levan Polysaccharide toward Transient Electronics

Ki Yoon Kwon, Ju Seung Lee, Gwan Jin Ko, Sung Hyuk Sunwoo, Sori Lee, Young Jin Jo, Chul Hee Choi, Suk Won Hwang, Tae il Kim

Research output: Contribution to journal › Article › peer-review

40 Citations (Scopus)

Abstract

New options in the material context of transient electronics are essential to create or expand potential applications and to progress in the face of technological challenges. A soft, transparent, and cost-effective polymer of levan polysaccharide that is capable of complete, programmable dissolution is described when immersed in water and implanted in an animal model. The results include chemical analysis, the kinetics of hydrolysis, and adjustable dissolution rates of levan, and a simple theoretical model of reactive diffusion governed by temperature. In vivo experiments of the levan represent nontoxicity and biocompatibility without any adverse reactions. On-demand, selective control of dissolution behaviors with an animal model demonstrates an effective triggering strategy to program the system's lifetime, providing the possibility of potential applications in envisioned areas such as bioresorbable electronic implants and drug release systems.

Original language	English
Article number	1801332
Journal	Small
Volume	14
Issue number	32
DOIs	https://doi.org/10.1002/smll.201801332
Publication status	Published - 2018 Aug 9

Bibliographical note

Funding Information:
This work was supported by Basic Science Research Program (NRF-2017R1D1A1B03033089) and (NRF-2017R1A5A1070259) through the National Research Foundation of Korea funded by the Ministry of Science, ICT, and Future Planning. G.-J.K. and S.-W.H. were supported by the KU-KIST Graduate School of Converging Science and Technology Program, KU Future Research Grant, and supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and Future Planning (grant NRF-2015R1C1A1A02037560 and NRF-2017R1E1A1A01075027).

Publisher Copyright:
© 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Keywords

biocompatible
biodegradable
implantable electronics
polysaccharide
transient electronics

ASJC Scopus subject areas

Biotechnology
Biomaterials
General Chemistry
General Materials Science

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title = "Biosafe, Eco-Friendly Levan Polysaccharide toward Transient Electronics",

abstract = "New options in the material context of transient electronics are essential to create or expand potential applications and to progress in the face of technological challenges. A soft, transparent, and cost-effective polymer of levan polysaccharide that is capable of complete, programmable dissolution is described when immersed in water and implanted in an animal model. The results include chemical analysis, the kinetics of hydrolysis, and adjustable dissolution rates of levan, and a simple theoretical model of reactive diffusion governed by temperature. In vivo experiments of the levan represent nontoxicity and biocompatibility without any adverse reactions. On-demand, selective control of dissolution behaviors with an animal model demonstrates an effective triggering strategy to program the system's lifetime, providing the possibility of potential applications in envisioned areas such as bioresorbable electronic implants and drug release systems.",

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AU - Jo, Young Jin

AU - Choi, Chul Hee

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Biosafe, Eco-Friendly Levan Polysaccharide toward Transient Electronics

Abstract

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Keywords

ASJC Scopus subject areas

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