Blood coagulation study using light-transmission method

Hyunjung Lim, Jeonghun Nam, Yongjin Lee, Shubin Xue, Seok Chung, Sehyun Shin

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    1 Citation (Scopus)

    Abstract

    Blood coagulation is one of the haemostatic processes, which results in a blood clot. It plays a substantial role in preventing the loss of blood. As a result of complex cascade of blood coagulation, fibrin is formed from fibrinogen, which can be detected using light transmission method. In this study, we introduced a novel microfluidic method to detect blood coagulation by measurement of the transmitted light intensity. The results indicated that the blood coagulation time is strongly related to RBC aggregation which was manipulated by adjusting hematocrit. Also, the results were compared with those measured by INRatio.

    Original languageEnglish
    Title of host publication14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
    Pages803-805
    Number of pages3
    Publication statusPublished - 2010
    Event14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 - Groningen, Netherlands
    Duration: 2010 Oct 32010 Oct 7

    Publication series

    Name14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
    Volume2

    Other

    Other14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
    Country/TerritoryNetherlands
    CityGroningen
    Period10/10/310/10/7

    Keywords

    • Blood coagulation
    • Light-transmission
    • Microfluidic chip

    ASJC Scopus subject areas

    • Control and Systems Engineering

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