TY - GEN
T1 - Blood coagulation study using light-transmission method
AU - Lim, Hyunjung
AU - Nam, Jeonghun
AU - Lee, Yongjin
AU - Xue, Shubin
AU - Chung, Seok
AU - Shin, Sehyun
PY - 2010
Y1 - 2010
N2 - Blood coagulation is one of the haemostatic processes, which results in a blood clot. It plays a substantial role in preventing the loss of blood. As a result of complex cascade of blood coagulation, fibrin is formed from fibrinogen, which can be detected using light transmission method. In this study, we introduced a novel microfluidic method to detect blood coagulation by measurement of the transmitted light intensity. The results indicated that the blood coagulation time is strongly related to RBC aggregation which was manipulated by adjusting hematocrit. Also, the results were compared with those measured by INRatio.
AB - Blood coagulation is one of the haemostatic processes, which results in a blood clot. It plays a substantial role in preventing the loss of blood. As a result of complex cascade of blood coagulation, fibrin is formed from fibrinogen, which can be detected using light transmission method. In this study, we introduced a novel microfluidic method to detect blood coagulation by measurement of the transmitted light intensity. The results indicated that the blood coagulation time is strongly related to RBC aggregation which was manipulated by adjusting hematocrit. Also, the results were compared with those measured by INRatio.
KW - Blood coagulation
KW - Light-transmission
KW - Microfluidic chip
UR - http://www.scopus.com/inward/record.url?scp=84884383829&partnerID=8YFLogxK
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M3 - Conference contribution
AN - SCOPUS:84884383829
SN - 9781618390622
T3 - 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
SP - 803
EP - 805
BT - 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
T2 - 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
Y2 - 3 October 2010 through 7 October 2010
ER -