Body Mass Index and Mortality

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4 Citations (Scopus)


Although the prevalence of obesity, a well-known risk factor for various chronic diseases such as hypertension, type 2 diabetes and dyslipidemia, is rapidly increasing worldwide, the association of obesity with all-cause mortality remains controversial. Many previous epidemiologic studies have demonstrated a U-shaped relationship between obesity and mortality, suggesting that there is an obesity paradox. However, recent large-scale meta-analyses found contradictory results that both overweight and obese subjects exhibited a significant increase in all-cause mortality. This review summarizes the key epidemiologic studies on the association of obesity with mortality and thoroughly examines the causes of the obesity paradox and the precautions needed in the interpretation of this clinical evidence.

Original languageEnglish
Pages (from-to)3-9
Number of pages7
JournalJournal of Obesity and Metabolic Syndrome
Issue number1
Publication statusPublished - 2017 Mar 1
Externally publishedYes


  • Body mass index
  • Mortality
  • Obesity
  • Waist circumference

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism


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