Bone scan appearance of renal osteodystrophy in diabetic chronic renal failure patients

Y. So, Young Hyun In Young Hyun, Soo Lee Dong Soo Lee, C. Ahn, J. K. Chung, S. Kim, Chul Lee Myung Chul Lee, Sang Lee Jung Sang Lee, C. S. Koh

    Research output: Contribution to journalArticlepeer-review

    2 Citations (Scopus)

    Abstract

    To investigate Tc-99m methylenediphosphonate (MDP) bone scan appearance in diabetic chronic renal failure patients, we compared the bone scan images of chronic renal failure patients with and without diabetes. The number of patients studied was 134, of whom 43 had diabetes. Two nuclear medicine physicians read Tc-99m MDP bone scan images and for six areas - the axial skeleton, long bone, skull and mandible, periarticular areas, costochondral junction, and sternum - assigned a score of either 1 or 0. The sums of scores were compared. We also performed multivariate analysis including sex, age, and serum creatinine level using analysis of covariance. DM group patients scored significantly lower (2.01 ± 0.95) than those of the non-DM group (3.26 ± 1.16). Analysis of covariance revealed that the lower DM group score was independent of sex, age, and serum creatinine level. The bone scans of diabetic chronic renal failure patients showed less Tc-99m MDP uptake than those of non-diabetic patients. Thus, diagnosing renal osteodystrophy in diabetic chronic renal failure patients on bone scan images could be difficult.

    Original languageEnglish
    Pages (from-to)417-421
    Number of pages5
    JournalRadiation Medicine - Medical Imaging and Radiation Oncology
    Volume16
    Issue number6
    Publication statusPublished - 1998

    Keywords

    • Bone scan
    • Diabetes mellitus
    • Renal osteodystrophy
    • Tc-99m methylenediphosphonate

    ASJC Scopus subject areas

    • Radiation
    • Radiology Nuclear Medicine and imaging
    • Oncology

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