Boronated thymidine analogues for boron neutron capture therapy

B. Thirumamagal; Jayaseharan Johnsamuel; Guirec Cosquer; Youngjoo Byun; Junhua Yan; Sureshbabu Narayanasamy; Werner Tjarks; Rolf Barth; Ashraf Al-Madhoun; Staffan Eriksson

doi:10.1080/15257770600793844

Boronated thymidine analogues for boron neutron capture therapy

B. Thirumamagal
, Jayaseharan Johnsamuel
, Guirec Cosquer
, Youngjoo Byun
, Junhua Yan
, Sureshbabu Narayanasamy
, Werner Tjarks^*
, Rolf Barth
, Ashraf Al-Madhoun
, Staffan Eriksson

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

Concise synthetic methods for synthesizing 3-carboranyl thymidine analogues (3CTAs) modified with cyclic and acyclic alcohols have been developed. The synthesis of these potential boron neutron capture therapy (BNCT) agents and their preliminary biological evaluation is described.

Original language	English
Pages (from-to)	861-866
Number of pages	6
Journal	Nucleosides, Nucleotides and Nucleic Acids
Volume	25
Issue number	8
DOIs	https://doi.org/10.1080/15257770600793844
Publication status	Published - 2006 Sept 1
Externally published	Yes

Keywords

3-Carboranyl Thymidine Analogues (3CTAs)
Boron Neutron Capture Therapy (BNCT)

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Genetics

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10.1080/15257770600793844

Cite this

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title = "Boronated thymidine analogues for boron neutron capture therapy",

abstract = "Concise synthetic methods for synthesizing 3-carboranyl thymidine analogues (3CTAs) modified with cyclic and acyclic alcohols have been developed. The synthesis of these potential boron neutron capture therapy (BNCT) agents and their preliminary biological evaluation is described.",

keywords = "3-Carboranyl Thymidine Analogues (3CTAs), Boron Neutron Capture Therapy (BNCT)",

author = "B. Thirumamagal and Jayaseharan Johnsamuel and Guirec Cosquer and Youngjoo Byun and Junhua Yan and Sureshbabu Narayanasamy and Werner Tjarks and Rolf Barth and Ashraf Al-Madhoun and Staffan Eriksson",

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TY - JOUR

T1 - Boronated thymidine analogues for boron neutron capture therapy

AU - Thirumamagal, B.

AU - Johnsamuel, Jayaseharan

AU - Cosquer, Guirec

AU - Byun, Youngjoo

AU - Yan, Junhua

AU - Narayanasamy, Sureshbabu

AU - Tjarks, Werner

AU - Barth, Rolf

AU - Al-Madhoun, Ashraf

AU - Eriksson, Staffan

PY - 2006/9/1

Y1 - 2006/9/1

N2 - Concise synthetic methods for synthesizing 3-carboranyl thymidine analogues (3CTAs) modified with cyclic and acyclic alcohols have been developed. The synthesis of these potential boron neutron capture therapy (BNCT) agents and their preliminary biological evaluation is described.

AB - Concise synthetic methods for synthesizing 3-carboranyl thymidine analogues (3CTAs) modified with cyclic and acyclic alcohols have been developed. The synthesis of these potential boron neutron capture therapy (BNCT) agents and their preliminary biological evaluation is described.

KW - 3-Carboranyl Thymidine Analogues (3CTAs)

KW - Boron Neutron Capture Therapy (BNCT)

UR - https://www.scopus.com/pages/publications/33746851620

U2 - 10.1080/15257770600793844

DO - 10.1080/15257770600793844

M3 - Article

C2 - 16901817

AN - SCOPUS:33746851620

SN - 1525-7770

VL - 25

SP - 861

EP - 866

JO - Nucleosides, Nucleotides and Nucleic Acids

JF - Nucleosides, Nucleotides and Nucleic Acids

IS - 8

ER -

Boronated thymidine analogues for boron neutron capture therapy

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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