Bulk synthesis of hydrogel anisotropic microparticles with degassed replica molding lithography

Hyeon Ung Kim, Yong Jun Lim, Nak jun Lee, Hyun Jee Lee, Ki Wan Bong

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A powerful method that allows mass production of anisotropic particles with simple equipment is particle replication in mold. However, polydimethylsiloxane (PDMS), which is generally used material in mold fabrication, is not spontaneously loaded by hydrophilic liquids due to the low wettability. We introduced degassed replica molding lithography, which technique is based on the gas-permeability of a degassed mold that acts as a suction pump to completely fill the molds with precursor liquids of any hydrophilicity. Therefore, defect free hydrogel microparticles can be produced by the technique which also allows high-resolution replication due to the reduced oxygen inhibition in the mold.

Original languageEnglish
Title of host publication23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
PublisherChemical and Biological Microsystems Society
Pages1104-1105
Number of pages2
ISBN (Electronic)9781733419000
Publication statusPublished - 2019
Event23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 - Basel, Switzerland
Duration: 2019 Oct 272019 Oct 31

Publication series

Name23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019

Conference

Conference23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
Country/TerritorySwitzerland
CityBasel
Period19/10/2719/10/31

Bibliographical note

Funding Information:
This work was supported by the National Research Foundation of Korea (NRF-2016R1A5A1010148, ERC).

Publisher Copyright:
© 2019 CBMS-0001.

Keywords

  • Gas-permeable
  • Hydrogels
  • Microparticles
  • Replica molding

ASJC Scopus subject areas

  • Bioengineering
  • Chemical Engineering (miscellaneous)

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