Calcium-alginate beads loaded with gallic acid: Preparation and characterization

Jinglei Li, Su Yeon Kim, Xiguang Chen, Hyun Jin Park

    Research output: Contribution to journalArticlepeer-review

    101 Citations (Scopus)

    Abstract

    Electrospray technique was used to prepare alginate beads with controllable size from about 200 μm to 1.3 mm by adjusting the working voltage. The encapsulation ability of alginate beads for gallic acid, a model hydrophilic phenolic compound, was investigated. Loading amount of gallic acid varied from 7 g/100 g-12 g/100 g among alginate beads samples. Fourier-transform infrared and differential scanning calorimetry result confirmed the inclusion of gallic acid. Moreover, no autoxidation of gallic acid was observed in the formulated alginate beads. Release profile result indicated that in simulated intestinal fluid the release was faster than that in gastric fluid. The release pattern was influenced by both loading amount of gallic acid and size of alginate beads. Our results suggest that alginate beads fabricated by electrospray method is a promising delivery system for water soluble phenolic compound like gallic acid.

    Original languageEnglish
    Pages (from-to)667-673
    Number of pages7
    JournalLWT - Food Science and Technology
    Volume68
    DOIs
    Publication statusPublished - 2016 May 1

    Bibliographical note

    Funding Information:
    This research was supported by Kyung-Nong Company, the International Research & Development Program of the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (MEST) of Korea (Grant No. 2012K1A3A1A20031356 ), a Korea University grant, Korea University.

    Publisher Copyright:
    © 2016 Elsevier Ltd.

    Keywords

    • Cross-linking
    • Electrospray
    • In vitro release
    • Size
    • Voltage

    ASJC Scopus subject areas

    • Food Science

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