Abstract
A series of calix[2]triazole[2]arenes, which are members of the heterocalixarene family, were generated by copper(I)-catalyzed Huisgen reaction in a one-pot synthesis. Their various conformational structures and physical properties were characterized by a computational, NMR spectroscopic, and X-ray structural investigation. Among six conformations, the 1,2-alternate conformation was found to be the most stable due to two intramolecular hydrogen bonds between the phenolic hydroxyl group and the triazole nitrogen atom. A series of calix[2]triazole[2]arenes, members of the heterocalixarene family, were synthesized and their various conformational structures were characterized on the basis of their X-ray crystal structures and NMR spectra.
Original language | English |
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Pages (from-to) | 4614-4623 |
Number of pages | 10 |
Journal | European Journal of Organic Chemistry |
Issue number | 21 |
DOIs | |
Publication status | Published - 2013 Jul |
Keywords
- Calixarenes
- Click chemistry
- Conformation analysis
- Structure elucidation
- Supramolecular chemistry
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry