Carbon nanotube pillar structures for human neural cell culture

Jin Woo Lee, Kyong Soo Lee, Byeong Kwon Ju, Hyun Jin Cho, Nae Sung Lee, Min Young Kim, Eun Hye Kim, Kyu Back Lee

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Human neuroblastoma cells were cultured and differentiated over patterned (dot, dash, and square pattern) pillar structures of multiwalled carbon nanotubes vertically grown on a SiO2 film-coated quartz substrate to observe cytoskeletal responses to the nanotube-based scaffold, especially filopodia activities. The cells over the square pattern formed a colony and showed short and thick filopodia protrusion as if the surface adhesion was unstable, whereas the cells over the dot or dash patterns showed long extensions of filopodia and unique serial branching onto the sidewall or over the tips of nanotube pillars. The results are important for the investigation of neural network regeneration using carbon nanotubes.

Original languageEnglish
Pages (from-to)2444-2448
Number of pages5
JournalJournal of Vacuum Science and Technology B: Microelectronics and Nanometer Structures
Issue number6
Publication statusPublished - 2009

Bibliographical note

Funding Information:
This work was partially supported by the National Research Laboratory (NRL, R0A-2007-000-20111-0) Program of the Ministry of Science and Technology (Korea Science and Engineering Foundation).

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Electrical and Electronic Engineering


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