TY - JOUR
T1 - Carbonic anhydrase for CO2 capture, conversion and utilization
AU - Talekar, Sachin
AU - Jo, Byung Hoon
AU - Dordick, Jonathan S.
AU - Kim, Jungbae
N1 - Funding Information:
J. Kim acknowledges a grant from the National Research Foundation of Korea (NRF) ( NRF-2020R1A2C3009649 ) funded by the Korea government Ministry of Science and ICT (MSIT, Korea) as well as the BK21 FOUR Program ( 4199990414461 ) funded by the Ministry of Education (MOE, Korea) . B. H. Jo acknowledges grants from the National Research Foundation of Korea (NRF) ( NRF-2021R1A5A8029490 and NRF-2021R1F1A1057310 ) funded by the Korea government Ministry of Science and ICT (MSIT) .
Publisher Copyright:
© 2021 Elsevier Ltd
PY - 2022/4
Y1 - 2022/4
N2 - Carbonic anhydrase (CA) enzymes, catalyzing the CO2 hydration at a high turnover number, can be employed in expediting CO2 capture, conversion and utilization to aid in carbon neutrality. Despite extensive research over the last decade, there remain challenges in CA-related technologies due to poor stability and suboptimal use of CAs. Herein, we discuss recent advances in CA stabilization by protein engineering and enzyme immobilization, and shed light on state-of-the-art of in vitro and in vivo CA-mediated CO2 conversion for improved production of value-added chemicals using CO2 as a feedstock.
AB - Carbonic anhydrase (CA) enzymes, catalyzing the CO2 hydration at a high turnover number, can be employed in expediting CO2 capture, conversion and utilization to aid in carbon neutrality. Despite extensive research over the last decade, there remain challenges in CA-related technologies due to poor stability and suboptimal use of CAs. Herein, we discuss recent advances in CA stabilization by protein engineering and enzyme immobilization, and shed light on state-of-the-art of in vitro and in vivo CA-mediated CO2 conversion for improved production of value-added chemicals using CO2 as a feedstock.
UR - http://www.scopus.com/inward/record.url?scp=85122161685&partnerID=8YFLogxK
U2 - 10.1016/j.copbio.2021.12.003
DO - 10.1016/j.copbio.2021.12.003
M3 - Review article
C2 - 34992045
AN - SCOPUS:85122161685
SN - 0958-1669
VL - 74
SP - 230
EP - 240
JO - Current Opinion in Biotechnology
JF - Current Opinion in Biotechnology
ER -