Carbonic anhydrase for CO2 capture, conversion and utilization

Sachin Talekar; Byung Hoon Jo; Jonathan S. Dordick; Jungbae Kim

doi:10.1016/j.copbio.2021.12.003

Carbonic anhydrase for CO₂ capture, conversion and utilization

Sachin Talekar, Byung Hoon Jo, Jonathan S. Dordick, Jungbae Kim

Department of Chemical and Biological Engineering

Research output: Contribution to journal › Review article › peer-review

32 Citations (Scopus)

Abstract

Carbonic anhydrase (CA) enzymes, catalyzing the CO₂ hydration at a high turnover number, can be employed in expediting CO₂ capture, conversion and utilization to aid in carbon neutrality. Despite extensive research over the last decade, there remain challenges in CA-related technologies due to poor stability and suboptimal use of CAs. Herein, we discuss recent advances in CA stabilization by protein engineering and enzyme immobilization, and shed light on state-of-the-art of in vitro and in vivo CA-mediated CO₂ conversion for improved production of value-added chemicals using CO₂ as a feedstock.

Original language	English
Pages (from-to)	230-240
Number of pages	11
Journal	Current Opinion in Biotechnology
Volume	74
DOIs	https://doi.org/10.1016/j.copbio.2021.12.003
Publication status	Published - 2022 Apr

Bibliographical note

Funding Information:
J. Kim acknowledges a grant from the National Research Foundation of Korea (NRF) ( NRF-2020R1A2C3009649 ) funded by the Korea government Ministry of Science and ICT (MSIT, Korea) as well as the BK21 FOUR Program ( 4199990414461 ) funded by the Ministry of Education (MOE, Korea) . B. H. Jo acknowledges grants from the National Research Foundation of Korea (NRF) ( NRF-2021R1A5A8029490 and NRF-2021R1F1A1057310 ) funded by the Korea government Ministry of Science and ICT (MSIT) .

Publisher Copyright:
© 2021 Elsevier Ltd

ASJC Scopus subject areas

Biotechnology
Bioengineering
Biomedical Engineering

Access to Document

10.1016/j.copbio.2021.12.003

Cite this

@article{8306bd7d59754b5b9506fb266335031d,

title = "Carbonic anhydrase for CO2 capture, conversion and utilization",

abstract = "Carbonic anhydrase (CA) enzymes, catalyzing the CO2 hydration at a high turnover number, can be employed in expediting CO2 capture, conversion and utilization to aid in carbon neutrality. Despite extensive research over the last decade, there remain challenges in CA-related technologies due to poor stability and suboptimal use of CAs. Herein, we discuss recent advances in CA stabilization by protein engineering and enzyme immobilization, and shed light on state-of-the-art of in vitro and in vivo CA-mediated CO2 conversion for improved production of value-added chemicals using CO2 as a feedstock.",

author = "Sachin Talekar and Jo, {Byung Hoon} and Dordick, {Jonathan S.} and Jungbae Kim",

note = "Funding Information: J. Kim acknowledges a grant from the National Research Foundation of Korea (NRF) ( NRF-2020R1A2C3009649 ) funded by the Korea government Ministry of Science and ICT (MSIT, Korea) as well as the BK21 FOUR Program ( 4199990414461 ) funded by the Ministry of Education (MOE, Korea) . B. H. Jo acknowledges grants from the National Research Foundation of Korea (NRF) ( NRF-2021R1A5A8029490 and NRF-2021R1F1A1057310 ) funded by the Korea government Ministry of Science and ICT (MSIT) . Publisher Copyright: {\textcopyright} 2021 Elsevier Ltd",

year = "2022",

month = apr,

doi = "10.1016/j.copbio.2021.12.003",

language = "English",

volume = "74",

pages = "230--240",

journal = "Current Opinion in Biotechnology",

issn = "0958-1669",

publisher = "Elsevier Limited",

}

TY - JOUR

T1 - Carbonic anhydrase for CO2 capture, conversion and utilization

AU - Talekar, Sachin

AU - Jo, Byung Hoon

AU - Dordick, Jonathan S.

AU - Kim, Jungbae

N1 - Funding Information: J. Kim acknowledges a grant from the National Research Foundation of Korea (NRF) ( NRF-2020R1A2C3009649 ) funded by the Korea government Ministry of Science and ICT (MSIT, Korea) as well as the BK21 FOUR Program ( 4199990414461 ) funded by the Ministry of Education (MOE, Korea) . B. H. Jo acknowledges grants from the National Research Foundation of Korea (NRF) ( NRF-2021R1A5A8029490 and NRF-2021R1F1A1057310 ) funded by the Korea government Ministry of Science and ICT (MSIT) . Publisher Copyright: © 2021 Elsevier Ltd

PY - 2022/4

Y1 - 2022/4

N2 - Carbonic anhydrase (CA) enzymes, catalyzing the CO2 hydration at a high turnover number, can be employed in expediting CO2 capture, conversion and utilization to aid in carbon neutrality. Despite extensive research over the last decade, there remain challenges in CA-related technologies due to poor stability and suboptimal use of CAs. Herein, we discuss recent advances in CA stabilization by protein engineering and enzyme immobilization, and shed light on state-of-the-art of in vitro and in vivo CA-mediated CO2 conversion for improved production of value-added chemicals using CO2 as a feedstock.

AB - Carbonic anhydrase (CA) enzymes, catalyzing the CO2 hydration at a high turnover number, can be employed in expediting CO2 capture, conversion and utilization to aid in carbon neutrality. Despite extensive research over the last decade, there remain challenges in CA-related technologies due to poor stability and suboptimal use of CAs. Herein, we discuss recent advances in CA stabilization by protein engineering and enzyme immobilization, and shed light on state-of-the-art of in vitro and in vivo CA-mediated CO2 conversion for improved production of value-added chemicals using CO2 as a feedstock.

UR - http://www.scopus.com/inward/record.url?scp=85122161685&partnerID=8YFLogxK

U2 - 10.1016/j.copbio.2021.12.003

DO - 10.1016/j.copbio.2021.12.003

M3 - Review article

C2 - 34992045

AN - SCOPUS:85122161685

SN - 0958-1669

VL - 74

SP - 230

EP - 240

JO - Current Opinion in Biotechnology

JF - Current Opinion in Biotechnology

ER -