Castleman's disease of the head and neck

Jae Jun Song, Myung Ho Jung, Jeong Soo Woo, Sung Won Chae, Soon Jae Hwang, Heung Man Lee

Research output: Contribution to journalReview articlepeer-review

26 Citations (Scopus)


Castleman's disease is an uncommon benign disease that causes progressive lymph node enlargement. We report 12 cases of Castleman's disease in the head and neck region in a retrospective review of the medical records of all patients with the pathological diagnosis of Castleman's disease during the period of 1993 through 2002. In the 12 patients, the neck was the most commonly involved site with 9 (75%) cases. Level III was the most common subsite (five cases). The most common sign in our study was an asymptomatic neck mass. No patient had any past histories that required medical attention. Preoperative work up such as fine-needle aspiration and radiographic study was not helpful for diagnostic confirmation. The histopathologic evaluation was the only way to make a definitive diagnosis. The histopathologic subtype of our study was hyaline-vascular type. Excision was curative for all cases. There was no evidence of recurrence with a minimum followup duration of 24 months.

Original languageEnglish
Pages (from-to)160-163
Number of pages4
JournalEuropean Archives of Oto-Rhino-Laryngology
Issue number2
Publication statusPublished - 2006 Feb


  • Asymptomatic neck mass
  • Castleman's disease
  • Head and neck

ASJC Scopus subject areas

  • Otorhinolaryngology


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