Abstract
Here, we present a simple method to generate type 1 collagen (COL1) microbeads which are uniform and size controllable and to coat cells on them with high cell viability. We show that COL1 microbead is suitable for making micro-scaled tissue unit and confirmed that morphological characteristics of COL1 microbead is dependent on cell types showing various cell-ECM interaction. We expect ECM microbeads can be applicable for not only tissue reconstitution, but also quantitative studies for cell-ECM interactions.
| Original language | English |
|---|---|
| Title of host publication | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 494-496 |
| Number of pages | 3 |
| ISBN (Print) | 9780979806476 |
| Publication status | Published - 2014 |
| Event | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States Duration: 2014 Oct 26 → 2014 Oct 30 |
Other
| Other | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 |
|---|---|
| Country/Territory | United States |
| City | San Antonio |
| Period | 14/10/26 → 14/10/30 |
Keywords
- Collagen
- Extracellular matrix
- Microbead
- Tissue engineering
ASJC Scopus subject areas
- Control and Systems Engineering