Cell type-selective imaging and profiling of newly synthesized proteomes by using puromycin analogues

Shubo Du; Danyang Wang; Jun Seok Lee; Bo Peng; Jingyan Ge; Shao Q. Yao

doi:10.1039/c7cc04536k

Cell type-selective imaging and profiling of newly synthesized proteomes by using puromycin analogues

Shubo Du
, Danyang Wang
, Jun Seok Lee
, Bo Peng
, Jingyan Ge^*
, Shao Q. Yao

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

We have developed a versatile antibody-assisted strategy for the imaging and profiling of newly synthesized proteomes in a cell-specific manner. This strategy remained highly selective even in heterogeneous co-cultured cells, thus enabling labeling and enrichment of nascent proteomes from targeted cells without the need for physical separation.

Original language	English
Pages (from-to)	8443-8446
Number of pages	4
Journal	Chemical Communications
Volume	53
Issue number	60
DOIs	https://doi.org/10.1039/c7cc04536k
Publication status	Published - 2017
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2017 The Royal Society of Chemistry.

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c7cc04536k

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title = "Cell type-selective imaging and profiling of newly synthesized proteomes by using puromycin analogues",

abstract = "We have developed a versatile antibody-assisted strategy for the imaging and profiling of newly synthesized proteomes in a cell-specific manner. This strategy remained highly selective even in heterogeneous co-cultured cells, thus enabling labeling and enrichment of nascent proteomes from targeted cells without the need for physical separation.",

author = "Shubo Du and Danyang Wang and Lee, \{Jun Seok\} and Bo Peng and Jingyan Ge and Yao, \{Shao Q.\}",

note = "Publisher Copyright: {\textcopyright} 2017 The Royal Society of Chemistry.",

year = "2017",

doi = "10.1039/c7cc04536k",

language = "English",

volume = "53",

pages = "8443--8446",

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publisher = "Royal Society of Chemistry",

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T1 - Cell type-selective imaging and profiling of newly synthesized proteomes by using puromycin analogues

AU - Du, Shubo

AU - Wang, Danyang

AU - Lee, Jun Seok

AU - Peng, Bo

AU - Ge, Jingyan

AU - Yao, Shao Q.

PY - 2017

Y1 - 2017

N2 - We have developed a versatile antibody-assisted strategy for the imaging and profiling of newly synthesized proteomes in a cell-specific manner. This strategy remained highly selective even in heterogeneous co-cultured cells, thus enabling labeling and enrichment of nascent proteomes from targeted cells without the need for physical separation.

AB - We have developed a versatile antibody-assisted strategy for the imaging and profiling of newly synthesized proteomes in a cell-specific manner. This strategy remained highly selective even in heterogeneous co-cultured cells, thus enabling labeling and enrichment of nascent proteomes from targeted cells without the need for physical separation.

UR - https://www.scopus.com/pages/publications/85026447986

U2 - 10.1039/c7cc04536k

DO - 10.1039/c7cc04536k

M3 - Article

C2 - 28702584

AN - SCOPUS:85026447986

SN - 1359-7345

VL - 53

SP - 8443

EP - 8446

JO - Chemical Communications

JF - Chemical Communications

IS - 60

ER -

Cell type-selective imaging and profiling of newly synthesized proteomes by using puromycin analogues

Abstract

Bibliographical note

ASJC Scopus subject areas

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