Cerebral syphilitic gumma mimicking a brain tumor in the relapse of secondary syphilis in a human immunodeficiency virus-negative patient

Young Kyung Yoon, Min Ja Kim, Yang Seok Chae, Shin Hyuk Kang

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)

Abstract

Diagnosis of cerebral syphilitic gumma is frequently determined at the time of surgery, because imaging and laboratory findings demonstrate the elusive results. A 59-year-old woman presenting dysarthria showed a mass on her brain computed tomography. She was first suspected of brain tumor, but histological results from surgical resection revealed cerebral gumma due to neurosyphilis. After operation, she presented fever and rash with an infiltration on a chest X-ray. Histological assessment of skin was consistent with syphilis. Fluorescent treponemal antibody absorbed test IgG in cerebrospinal fluid was positive. She was successfully treated with ceftriaxone for 14 days.

Original languageEnglish
Pages (from-to)197-200
Number of pages4
JournalJournal of Korean Neurosurgical Society
Volume53
Issue number3
DOIs
Publication statusPublished - 2013

Keywords

  • Ceftriaxone
  • Gummatous neurosyphilis
  • HIV negative
  • Latent syphilis

ASJC Scopus subject areas

  • Surgery
  • Neuroscience(all)
  • Clinical Neurology

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