Cerebral syphilitic gumma mimicking a brain tumor in the relapse of secondary syphilis in a human immunodeficiency virus-negative patient

Young Kyung Yoon, Min Ja Kim, Yang Seok Chae, Shin Hyuk Kang

    Research output: Contribution to journalArticlepeer-review

    21 Citations (Scopus)

    Abstract

    Diagnosis of cerebral syphilitic gumma is frequently determined at the time of surgery, because imaging and laboratory findings demonstrate the elusive results. A 59-year-old woman presenting dysarthria showed a mass on her brain computed tomography. She was first suspected of brain tumor, but histological results from surgical resection revealed cerebral gumma due to neurosyphilis. After operation, she presented fever and rash with an infiltration on a chest X-ray. Histological assessment of skin was consistent with syphilis. Fluorescent treponemal antibody absorbed test IgG in cerebrospinal fluid was positive. She was successfully treated with ceftriaxone for 14 days.

    Original languageEnglish
    Pages (from-to)197-200
    Number of pages4
    JournalJournal of Korean Neurosurgical Society
    Volume53
    Issue number3
    DOIs
    Publication statusPublished - 2013

    Keywords

    • Ceftriaxone
    • Gummatous neurosyphilis
    • HIV negative
    • Latent syphilis

    ASJC Scopus subject areas

    • Surgery
    • General Neuroscience
    • Clinical Neurology

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