Change in body surface temperature as an ancillary measurement to motor evoked potentials

J. H. Yang; S. W. Suh; Y. S. Park; J. H. Lee; B. K. Park; C. H. Ham; J. W. Choi

doi:10.1038/sc.2015.90

Change in body surface temperature as an ancillary measurement to motor evoked potentials

J. H. Yang, S. W. Suh, Y. S. Park, J. H. Lee, B. K. Park, C. H. Ham, J. W. Choi

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Study design:Experimental study.Objectives:To study the role of surface temperature as an adjunct to motor evoked potentials (MEPs) in rabbit spinal cord injury (SCI) model.Setting:Department of Orthopedics, Korea University Guro Hospital, Seoul, Korea.Methods:Rabbits (n=18) were divided into Complete (n=9) and Incomplete (n=9) SCI groups. Complete SCI was defined as being non-responsive to a wake-up test with loss of MEPs after transection of spinal cord. Incomplete SCI was defined as being responsive to a wake-up test with significant attenuation (≥80%) of MEPs after impaction on spinal cord. Surface temperature of upper and lower extremities, core temperature and MEPs signals were checked before, during and after SCI for 20 min. A wake-up test was conducted and spinal cord was histologicaly evaluated.Results:Experimental conditions between the two groups were statistically similar (P>0.005 for all values). After SCI, upper extremity temperatures did not change in either group (P>0.005); however, the surface temperature of the lower extremities in the Complete SCI Group elevated to 1.7±0.5 °C in comparison to 0.5±0.1 °C in the Incomplete SCI Group (P<0.001). The scores of wake-up test in the Incomplete SCI Group were significantly different from that of the Complete SCI Group (P<0.001), while white and gray matter damage was variable on histology.Conclusions:Monitoring of changes of body surface temperature of the lower extremities can be potentially used to identify the completeness of SCI in a rabbit model.

Original language	English
Pages (from-to)	827-834
Number of pages	8
Journal	Spinal Cord
Volume	53
Issue number	11
DOIs	https://doi.org/10.1038/sc.2015.90
Publication status	Published - 2015 Nov 1

Bibliographical note

Funding Information:
This study was supported by a grant of the Korea Health Technology R&D Project, Ministry of Health & Welfare, Republic of Korea (HI11C0388). This study was performed under the approval of the IACUC (Institutional Animal Care and Use Committee, KU12129). All experimental procedures, protocols and treatment of experimental animals were performed under the control of the IACUC. This study was performed in the Korea University Guro Hospital.

Publisher Copyright:
© 2015 International Spinal Cord Society.

ASJC Scopus subject areas

Rehabilitation
Neurology
Clinical Neurology

Access to Document

10.1038/sc.2015.90

Cite this

@article{08e83767be304ec49a091e838f63c463,

title = "Change in body surface temperature as an ancillary measurement to motor evoked potentials",

abstract = "Study design:Experimental study.Objectives:To study the role of surface temperature as an adjunct to motor evoked potentials (MEPs) in rabbit spinal cord injury (SCI) model.Setting:Department of Orthopedics, Korea University Guro Hospital, Seoul, Korea.Methods:Rabbits (n=18) were divided into Complete (n=9) and Incomplete (n=9) SCI groups. Complete SCI was defined as being non-responsive to a wake-up test with loss of MEPs after transection of spinal cord. Incomplete SCI was defined as being responsive to a wake-up test with significant attenuation (≥80%) of MEPs after impaction on spinal cord. Surface temperature of upper and lower extremities, core temperature and MEPs signals were checked before, during and after SCI for 20 min. A wake-up test was conducted and spinal cord was histologicaly evaluated.Results:Experimental conditions between the two groups were statistically similar (P>0.005 for all values). After SCI, upper extremity temperatures did not change in either group (P>0.005); however, the surface temperature of the lower extremities in the Complete SCI Group elevated to 1.7±0.5 °C in comparison to 0.5±0.1 °C in the Incomplete SCI Group (P<0.001). The scores of wake-up test in the Incomplete SCI Group were significantly different from that of the Complete SCI Group (P<0.001), while white and gray matter damage was variable on histology.Conclusions:Monitoring of changes of body surface temperature of the lower extremities can be potentially used to identify the completeness of SCI in a rabbit model.",

author = "Yang, {J. H.} and Suh, {S. W.} and Park, {Y. S.} and Lee, {J. H.} and Park, {B. K.} and Ham, {C. H.} and Choi, {J. W.}",

note = "Funding Information: This study was supported by a grant of the Korea Health Technology R&D Project, Ministry of Health & Welfare, Republic of Korea (HI11C0388). This study was performed under the approval of the IACUC (Institutional Animal Care and Use Committee, KU12129). All experimental procedures, protocols and treatment of experimental animals were performed under the control of the IACUC. This study was performed in the Korea University Guro Hospital. Publisher Copyright: {\textcopyright} 2015 International Spinal Cord Society.",

year = "2015",

month = nov,

day = "1",

doi = "10.1038/sc.2015.90",

language = "English",

volume = "53",

pages = "827--834",

journal = "Spinal Cord",

issn = "1362-4393",

publisher = "Springer Nature",

number = "11",

}

TY - JOUR

T1 - Change in body surface temperature as an ancillary measurement to motor evoked potentials

AU - Yang, J. H.

AU - Suh, S. W.

AU - Park, Y. S.

AU - Lee, J. H.

AU - Park, B. K.

AU - Ham, C. H.

AU - Choi, J. W.

N1 - Funding Information: This study was supported by a grant of the Korea Health Technology R&D Project, Ministry of Health & Welfare, Republic of Korea (HI11C0388). This study was performed under the approval of the IACUC (Institutional Animal Care and Use Committee, KU12129). All experimental procedures, protocols and treatment of experimental animals were performed under the control of the IACUC. This study was performed in the Korea University Guro Hospital. Publisher Copyright: © 2015 International Spinal Cord Society.

PY - 2015/11/1

Y1 - 2015/11/1

N2 - Study design:Experimental study.Objectives:To study the role of surface temperature as an adjunct to motor evoked potentials (MEPs) in rabbit spinal cord injury (SCI) model.Setting:Department of Orthopedics, Korea University Guro Hospital, Seoul, Korea.Methods:Rabbits (n=18) were divided into Complete (n=9) and Incomplete (n=9) SCI groups. Complete SCI was defined as being non-responsive to a wake-up test with loss of MEPs after transection of spinal cord. Incomplete SCI was defined as being responsive to a wake-up test with significant attenuation (≥80%) of MEPs after impaction on spinal cord. Surface temperature of upper and lower extremities, core temperature and MEPs signals were checked before, during and after SCI for 20 min. A wake-up test was conducted and spinal cord was histologicaly evaluated.Results:Experimental conditions between the two groups were statistically similar (P>0.005 for all values). After SCI, upper extremity temperatures did not change in either group (P>0.005); however, the surface temperature of the lower extremities in the Complete SCI Group elevated to 1.7±0.5 °C in comparison to 0.5±0.1 °C in the Incomplete SCI Group (P<0.001). The scores of wake-up test in the Incomplete SCI Group were significantly different from that of the Complete SCI Group (P<0.001), while white and gray matter damage was variable on histology.Conclusions:Monitoring of changes of body surface temperature of the lower extremities can be potentially used to identify the completeness of SCI in a rabbit model.

AB - Study design:Experimental study.Objectives:To study the role of surface temperature as an adjunct to motor evoked potentials (MEPs) in rabbit spinal cord injury (SCI) model.Setting:Department of Orthopedics, Korea University Guro Hospital, Seoul, Korea.Methods:Rabbits (n=18) were divided into Complete (n=9) and Incomplete (n=9) SCI groups. Complete SCI was defined as being non-responsive to a wake-up test with loss of MEPs after transection of spinal cord. Incomplete SCI was defined as being responsive to a wake-up test with significant attenuation (≥80%) of MEPs after impaction on spinal cord. Surface temperature of upper and lower extremities, core temperature and MEPs signals were checked before, during and after SCI for 20 min. A wake-up test was conducted and spinal cord was histologicaly evaluated.Results:Experimental conditions between the two groups were statistically similar (P>0.005 for all values). After SCI, upper extremity temperatures did not change in either group (P>0.005); however, the surface temperature of the lower extremities in the Complete SCI Group elevated to 1.7±0.5 °C in comparison to 0.5±0.1 °C in the Incomplete SCI Group (P<0.001). The scores of wake-up test in the Incomplete SCI Group were significantly different from that of the Complete SCI Group (P<0.001), while white and gray matter damage was variable on histology.Conclusions:Monitoring of changes of body surface temperature of the lower extremities can be potentially used to identify the completeness of SCI in a rabbit model.

UR - http://www.scopus.com/inward/record.url?scp=84947031195&partnerID=8YFLogxK

U2 - 10.1038/sc.2015.90

DO - 10.1038/sc.2015.90

M3 - Article

C2 - 26123207

AN - SCOPUS:84947031195

SN - 1362-4393

VL - 53

SP - 827

EP - 834

JO - Spinal Cord

JF - Spinal Cord

IS - 11

ER -

Change in body surface temperature as an ancillary measurement to motor evoked potentials

Abstract

Bibliographical note

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this