TY - GEN
T1 - Chemically controlled insect cyborgs using implantable multi-reservoir microfluidic device
AU - Chung, Aram J.
AU - Cordovez, Bernardo
AU - Reissman, Timothy
AU - MacCurdy, Robert
AU - Garcia, Ephrahim
AU - Erickson, David
PY - 2009
Y1 - 2009
N2 - This work describes to directly and reversibly control Manduca Sexta flight metabolics using electrochemically driven multi-reservoir microfluidic devices taking a step towards a method of creating a small scale aircraft based on living systems. In our previous work [1], we demonstrated modulations of the internal metabolic rates. Briefly, we could retard or completely paralyze insects' behavior over timescales ranging from minutes to hours. Here we present more precise insect flight control including stimulation of moths of Trehalose, Oxotremorine-M (Oxo-M), and L-Glutamic acid (LGA), and show details of newly developed multi-reservoir drug delivery device which allows for various physiological responses.
AB - This work describes to directly and reversibly control Manduca Sexta flight metabolics using electrochemically driven multi-reservoir microfluidic devices taking a step towards a method of creating a small scale aircraft based on living systems. In our previous work [1], we demonstrated modulations of the internal metabolic rates. Briefly, we could retard or completely paralyze insects' behavior over timescales ranging from minutes to hours. Here we present more precise insect flight control including stimulation of moths of Trehalose, Oxotremorine-M (Oxo-M), and L-Glutamic acid (LGA), and show details of newly developed multi-reservoir drug delivery device which allows for various physiological responses.
KW - Electrochemical drug delivery
KW - Immature Stage implanted microfluidics
KW - Insect cyborg
KW - Metabolic control
UR - http://www.scopus.com/inward/record.url?scp=84901781531&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84901781531&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84901781531
SN - 9780979806421
T3 - Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
SP - 198
EP - 200
BT - Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PB - Chemical and Biological Microsystems Society
T2 - 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009
Y2 - 1 November 2009 through 5 November 2009
ER -