Clinical effect of add-on Primovist-enhanced magnetic resonance imaging on preoperative tumor staging in hepatocellular carcinoma patients

  • Young Joo Jin
  • , Jin Woo Lee*
  • , Oh Sang Kwon
  • , Young Kul Jung
  • , Jung Hyun Kwon
  • , Jeong Won Jang
  • , Young Seok Kim
  • , Tae Hun Kim
  • , Yong Sun Jeon
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Background/Aims: We analyzed the incidence of change of Barcelona Clinic Liver Cancer (BCLC) stage after add-on Primovist-enhanced magnetic resonance imaging (MRI) in hepatocellular carcinoma (HCC) patients with Barcelona Clinic Liver Cancer stage 0 or A as determined by liver dynamic computed tomography (LDCT). Methods: A total of 166 patients enrolled prospectively between August 2012 and December 2014 were retrospectively analyzed. The rates of stage change after Primovist-enhanced MRI and the treatment finally adopted in patients with stage change were evaluated. Results: Of the 166 patients, 24 (18.6%) had truly new HCCs. Forty-six (27.7%) and 120 (72.3%) patients had BCLC stages 0 and A, respectively, before Primovist-enhanced MRI, but after Primovist-enhanced MRI, 28 (16.9%), 134 (80.7%), and 4 (2.4%) patients had BCLC stages 0, A, and B, respectively. Tumor stage changed in 22 (13.3%) patients, from 0 to A (18, 39.1%) or A to B (4, 3.3%). Conclusions: Add-on Primovist-enhanced magnetic resonance imaging can change BCLC stage with 13.3% in patients with BCLC 0 or A staged HCC, as determined by LDCT. J. Surg. Oncol. 2016;114:106–111.

Original languageEnglish
Pages (from-to)106-111
Number of pages6
JournalJournal of Surgical Oncology
Volume114
Issue number1
DOIs
Publication statusPublished - 2016 Jul 1

Bibliographical note

Publisher Copyright:
© 2016 Wiley Periodicals, Inc.

Keywords

  • Barcelona clinic liver cancer
  • hepatocellular carcinoma
  • liver dynamic computed tomography
  • primovist-enhanced magnetic resonance imaging

ASJC Scopus subject areas

  • Surgery
  • Oncology

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