Clinical Features of Influenza and Acute Respiratory Illness in Older Adults at Least 50 Years of Age in an Outpatient Setting in the Republic of Korea: A Prospective, Observational, Cohort Study

Woo Joo Kim, Jin Soo Lee, Chang Kyu Lee, Hee Jin Cheong, Mijeong Kim, Javier Sawchik Monegal, Rute Carneiro, Moe H. Kyaw, Haguinet François Haguinet, Riju Ray, Gonçalo Matias

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Two prospective, multi-centre, observational studies (GlaxoSmithKline [GSK] identifier No. 110938 and 112519) were performed over 2 influenza seasons (2007-2008 and 2008-2009) in the Republic of Korea (ROK) with the aim to evaluate the burden of laboratoryconfirmed influenza (LCI) in patients = 50 years of age seeking medical attention for acute respiratory illness (ARI). The median participant age was 58 years in the 2007-2008 season and 60 years in the 2008-2009 season. LCI was observed in 101/346 (29.2%) of ARI patients in the 2007-2008 season and in 166/443 (37.5%) of ARI patients in the 2008- 2009 season. Compared to patients with non-influenza ARI, those with LCI had higher rates of decreased daily activities (60.4% vs. 32.9% in 2007-2008 and 46.4% vs. 25.8% in 2008-2009), work absenteeism (51.1% vs. 25.6% and 14.4% vs. 7.7%), and longer duration of illness. These results indicated that influenza is an important cause of ARI in adults aged 50 and older causing more severe illness than non-influenza related ARI.

    Original languageEnglish
    Pages (from-to)407-414
    Number of pages8
    JournalJournal of Korean medical science
    Volume32
    Issue number3
    DOIs
    Publication statusPublished - 2017

    Bibliographical note

    Publisher Copyright:
    © 2017 The Korean Academy of Medical Sciences.

    Keywords

    • Acute Respiratory Illness
    • Adult
    • Epidemiology
    • Influenza
    • Republic of Korea

    ASJC Scopus subject areas

    • General Medicine

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