Clinical safety of drug-eluting stents in the Korea acute myocardial infarction registry

Rok Lee Sang; Ho Jeong Myung; Keun Ahn Young; Chull Chae Shung; Ho Hur Seung; Jo Kim Young; Whan Seong In; Keon Chae Jei; Jong Hong Taek; Young Rhew Jae; Chan Cho Myeong; Ho Bae Jang; Woon Rha Seung; Jin Kim Chong; Soo Jang Yang; Jung Park Seung; Hyun Kim Jong; Hoon Choi Dong; Il Kim Doo; Ho Chae In; Han Yoon Jung; Kwon Koo Bon; Ok Kim Byung; Yong Lee Myoung; Sik Kim Kee; Yong Hwang Jin; Kyu Oh Seok; Hee Lee Nae; Tae Jeong Kyoung; Jea Tahk Seung; Soo Park Keum; Rok Han Kyoo; Hoon Ahn Tae; Hyun Kim Moo; Bae Seung Ki; Sung Chung Wook; Young Yang Ju; Yun Rhim Chong; Cheol Gwon Hyeon; Wook Park Seong; Youp Koh Young; Jae Joo Seung; Joong Kim Soo; Kyu Jin Dong; Man Cho Jin; Gwan Cho Jeong

doi:10.1253/circj.72.392

Clinical safety of drug-eluting stents in the Korea acute myocardial infarction registry

Rok Lee Sang, Ho Jeong Myung, Keun Ahn Young, Chull Chae Shung, Ho Hur Seung, Jo Kim Young, Whan Seong In, Keon Chae Jei, Jong Hong Taek, Young Rhew Jae, Chan Cho Myeong, Ho Bae Jang, Woon Rha Seung, Jin Kim Chong, Soo Jang Yang, Jung Park Seung, Hyun Kim Jong, Hoon Choi Dong, Il Kim Doo, Ho Chae InHan Yoon Jung, Kwon Koo Bon, Ok Kim Byung, Yong Lee Myoung, Sik Kim Kee, Yong Hwang Jin, Kyu Oh Seok, Hee Lee Nae, Tae Jeong Kyoung, Jea Tahk Seung, Soo Park Keum, Rok Han Kyoo, Hoon Ahn Tae, Hyun Kim Moo, Bae Seung Ki, Sung Chung Wook, Young Yang Ju, Yun Rhim Chong, Cheol Gwon Hyeon, Wook Park Seong, Youp Koh Young, Jae Joo Seung, Joong Kim Soo, Kyu Jin Dong, Man Cho Jin, Gwan Cho Jeong

Department of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

42 Citations (Scopus)

Abstract

Background: Percutaneous coronary intervention (PCI) with drug-eluting stents (DES) may be useful in patients with acute myocardial infarction (AMI), but safety issues still need to be solved. This study was undertaken to investigate the incidence of major adverse cardiac events (MACE) and stent thrombosis in DES-implanted AMI patients in real-life clinical practice. Methods and Results: On-line registry of AMI cases at the web site www.kamir.or.kr has been performed in 41 primary PCI centers in Korea and between November 2005 and September 2006, 1,541 surviving patients who had been implanted with either Cypher® or Taxus® stents were enrolled for analysis during a 6-month clinical follow-up. There were 2 groups: group I [834 patients, 61.9±11.9 years: sirolimus-eluting stent (Cypher®)], group H [707 patients, 62.9±12.0 years: paclitaxel-eluting stent (Taxus®)]. At both 1 and 6 months the incidence of MACE was not significantly different between the 2 groups. There were 17 cases of stent thrombosis, but the incidence of stent thrombosis was not significantly different between the2 groups (group I:II=9 (1.1%): 8 (1.1%), p=1.000). The stent type, length, number, lesion complexity and diabetes were not significant for the incidence of MACE or stent thrombosis after adjustment. Conclusion: MACE and stent thrombosis rates did not differ between 2 types of DES identified in Korea Acute Myocardial Infarction Registry (KAMIR). DES can be used in patients with AMI with a relatively low 6-month MACE rate.

Original language	English
Pages (from-to)	392-398
Number of pages	7
Journal	Circulation Journal
Volume	72
Issue number	3
DOIs	https://doi.org/10.1253/circj.72.392
Publication status	Published - 2008

Keywords

Angioplasty
Korea
Major adverse cardiac events (MACE)
Myocardial infarction
Stents

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1253/circj.72.392

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Sang, R. L., Myung, H. J., Young, K. A., Shung, C. C., Seung, H. H., Young, J. K., In, W. S., Jei, K. C., Taek, J. H., Jae, Y. R., Myeong, C. C., Jang, H. B., Seung, W. R., Chong, J. K., Yang, S. J., Seung, J. P., Jong, H. K., Dong, H. C., Doo, I. K., ... Jeong, G. C. (2008). Clinical safety of drug-eluting stents in the Korea acute myocardial infarction registry. Circulation Journal, 72(3), 392-398. https://doi.org/10.1253/circj.72.392

Sang, RL, Myung, HJ, Young, KA, Shung, CC, Seung, HH, Young, JK, In, WS, Jei, KC, Taek, JH, Jae, YR, Myeong, CC, Jang, HB, Seung, WR, Chong, JK, Yang, SJ, Seung, JP, Jong, HK, Dong, HC, Doo, IK, In, HC, Jung, HY, Bon, KK, Byung, OK, Myoung, YL, Kee, SK, Jin, YH, Seok, KO, Nae, HL, Kyoung, TJ, Seung, JT, Keum, SP, Kyoo, RH, Tae, HA, Moo, HK, Ki, BS, Wook, SC, Ju, YY, Chong, YR, Hyeon, CG, Seong, WP, Young, YK, Seung, JJ, Soo, JK, Dong, KJ, Jin, MC & Jeong, GC 2008, 'Clinical safety of drug-eluting stents in the Korea acute myocardial infarction registry', Circulation Journal, vol. 72, no. 3, pp. 392-398. https://doi.org/10.1253/circj.72.392

@article{0a1a3dad21114f7a92ced62aedc8ba4d,

title = "Clinical safety of drug-eluting stents in the Korea acute myocardial infarction registry",

abstract = "Background: Percutaneous coronary intervention (PCI) with drug-eluting stents (DES) may be useful in patients with acute myocardial infarction (AMI), but safety issues still need to be solved. This study was undertaken to investigate the incidence of major adverse cardiac events (MACE) and stent thrombosis in DES-implanted AMI patients in real-life clinical practice. Methods and Results: On-line registry of AMI cases at the web site www.kamir.or.kr has been performed in 41 primary PCI centers in Korea and between November 2005 and September 2006, 1,541 surviving patients who had been implanted with either Cypher{\textregistered} or Taxus{\textregistered} stents were enrolled for analysis during a 6-month clinical follow-up. There were 2 groups: group I [834 patients, 61.9±11.9 years: sirolimus-eluting stent (Cypher{\textregistered})], group H [707 patients, 62.9±12.0 years: paclitaxel-eluting stent (Taxus{\textregistered})]. At both 1 and 6 months the incidence of MACE was not significantly different between the 2 groups. There were 17 cases of stent thrombosis, but the incidence of stent thrombosis was not significantly different between the2 groups (group I:II=9 (1.1%): 8 (1.1%), p=1.000). The stent type, length, number, lesion complexity and diabetes were not significant for the incidence of MACE or stent thrombosis after adjustment. Conclusion: MACE and stent thrombosis rates did not differ between 2 types of DES identified in Korea Acute Myocardial Infarction Registry (KAMIR). DES can be used in patients with AMI with a relatively low 6-month MACE rate.",

keywords = "Angioplasty, Korea, Major adverse cardiac events (MACE), Myocardial infarction, Stents",

author = "Sang, {Rok Lee} and Myung, {Ho Jeong} and Young, {Keun Ahn} and Shung, {Chull Chae} and Seung, {Ho Hur} and Young, {Jo Kim} and In, {Whan Seong} and Jei, {Keon Chae} and Taek, {Jong Hong} and Jae, {Young Rhew} and Myeong, {Chan Cho} and Jang, {Ho Bae} and Seung, {Woon Rha} and Chong, {Jin Kim} and Yang, {Soo Jang} and Seung, {Jung Park} and Jong, {Hyun Kim} and Dong, {Hoon Choi} and Doo, {Il Kim} and In, {Ho Chae} and Jung, {Han Yoon} and Bon, {Kwon Koo} and Byung, {Ok Kim} and Myoung, {Yong Lee} and Kee, {Sik Kim} and Jin, {Yong Hwang} and Seok, {Kyu Oh} and Nae, {Hee Lee} and Kyoung, {Tae Jeong} and Seung, {Jea Tahk} and Keum, {Soo Park} and Kyoo, {Rok Han} and Tae, {Hoon Ahn} and Moo, {Hyun Kim} and Ki, {Bae Seung} and Wook, {Sung Chung} and Ju, {Young Yang} and Chong, {Yun Rhim} and Hyeon, {Cheol Gwon} and Seong, {Wook Park} and Young, {Youp Koh} and Seung, {Jae Joo} and Soo, {Joong Kim} and Dong, {Kyu Jin} and Jin, {Man Cho} and Jeong, {Gwan Cho}",

year = "2008",

doi = "10.1253/circj.72.392",

language = "English",

volume = "72",

pages = "392--398",

journal = "Circulation Journal",

issn = "1346-9843",

publisher = "Japanese Circulation Society",

number = "3",

}

TY - JOUR

T1 - Clinical safety of drug-eluting stents in the Korea acute myocardial infarction registry

AU - Sang, Rok Lee

AU - Myung, Ho Jeong

AU - Young, Keun Ahn

AU - Shung, Chull Chae

AU - Seung, Ho Hur

AU - Young, Jo Kim

AU - In, Whan Seong

AU - Jei, Keon Chae

AU - Taek, Jong Hong

AU - Jae, Young Rhew

AU - Myeong, Chan Cho

AU - Jang, Ho Bae

AU - Seung, Woon Rha

AU - Chong, Jin Kim

AU - Yang, Soo Jang

AU - Seung, Jung Park

AU - Jong, Hyun Kim

AU - Dong, Hoon Choi

AU - Doo, Il Kim

AU - In, Ho Chae

AU - Jung, Han Yoon

AU - Bon, Kwon Koo

AU - Byung, Ok Kim

AU - Myoung, Yong Lee

AU - Kee, Sik Kim

AU - Jin, Yong Hwang

AU - Seok, Kyu Oh

AU - Nae, Hee Lee

AU - Kyoung, Tae Jeong

AU - Seung, Jea Tahk

AU - Keum, Soo Park

AU - Kyoo, Rok Han

AU - Tae, Hoon Ahn

AU - Moo, Hyun Kim

AU - Ki, Bae Seung

AU - Wook, Sung Chung

AU - Ju, Young Yang

AU - Chong, Yun Rhim

AU - Hyeon, Cheol Gwon

AU - Seong, Wook Park

AU - Young, Youp Koh

AU - Seung, Jae Joo

AU - Soo, Joong Kim

AU - Dong, Kyu Jin

AU - Jin, Man Cho

AU - Jeong, Gwan Cho

PY - 2008

Y1 - 2008

N2 - Background: Percutaneous coronary intervention (PCI) with drug-eluting stents (DES) may be useful in patients with acute myocardial infarction (AMI), but safety issues still need to be solved. This study was undertaken to investigate the incidence of major adverse cardiac events (MACE) and stent thrombosis in DES-implanted AMI patients in real-life clinical practice. Methods and Results: On-line registry of AMI cases at the web site www.kamir.or.kr has been performed in 41 primary PCI centers in Korea and between November 2005 and September 2006, 1,541 surviving patients who had been implanted with either Cypher® or Taxus® stents were enrolled for analysis during a 6-month clinical follow-up. There were 2 groups: group I [834 patients, 61.9±11.9 years: sirolimus-eluting stent (Cypher®)], group H [707 patients, 62.9±12.0 years: paclitaxel-eluting stent (Taxus®)]. At both 1 and 6 months the incidence of MACE was not significantly different between the 2 groups. There were 17 cases of stent thrombosis, but the incidence of stent thrombosis was not significantly different between the2 groups (group I:II=9 (1.1%): 8 (1.1%), p=1.000). The stent type, length, number, lesion complexity and diabetes were not significant for the incidence of MACE or stent thrombosis after adjustment. Conclusion: MACE and stent thrombosis rates did not differ between 2 types of DES identified in Korea Acute Myocardial Infarction Registry (KAMIR). DES can be used in patients with AMI with a relatively low 6-month MACE rate.

AB - Background: Percutaneous coronary intervention (PCI) with drug-eluting stents (DES) may be useful in patients with acute myocardial infarction (AMI), but safety issues still need to be solved. This study was undertaken to investigate the incidence of major adverse cardiac events (MACE) and stent thrombosis in DES-implanted AMI patients in real-life clinical practice. Methods and Results: On-line registry of AMI cases at the web site www.kamir.or.kr has been performed in 41 primary PCI centers in Korea and between November 2005 and September 2006, 1,541 surviving patients who had been implanted with either Cypher® or Taxus® stents were enrolled for analysis during a 6-month clinical follow-up. There were 2 groups: group I [834 patients, 61.9±11.9 years: sirolimus-eluting stent (Cypher®)], group H [707 patients, 62.9±12.0 years: paclitaxel-eluting stent (Taxus®)]. At both 1 and 6 months the incidence of MACE was not significantly different between the 2 groups. There were 17 cases of stent thrombosis, but the incidence of stent thrombosis was not significantly different between the2 groups (group I:II=9 (1.1%): 8 (1.1%), p=1.000). The stent type, length, number, lesion complexity and diabetes were not significant for the incidence of MACE or stent thrombosis after adjustment. Conclusion: MACE and stent thrombosis rates did not differ between 2 types of DES identified in Korea Acute Myocardial Infarction Registry (KAMIR). DES can be used in patients with AMI with a relatively low 6-month MACE rate.

KW - Angioplasty

KW - Korea

KW - Major adverse cardiac events (MACE)

KW - Myocardial infarction

KW - Stents

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U2 - 10.1253/circj.72.392

DO - 10.1253/circj.72.392

M3 - Article

C2 - 18296834

AN - SCOPUS:42649119442

SN - 1346-9843

VL - 72

SP - 392

EP - 398

JO - Circulation Journal

JF - Circulation Journal

IS - 3

ER -

Clinical safety of drug-eluting stents in the Korea acute myocardial infarction registry

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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