TY - JOUR
T1 - Clinical validation of the psychotic depression assessment scale, hamilton depression rating scale-6, and brief psychiatric rating scale-5
T2 - Results from the clinical research center for depression study
AU - Park, Seon Cheol
AU - Jang, Eun Young
AU - Kim, Jae Min
AU - Jun, Tae Youn
AU - Lee, Min-Soo
AU - Kim, Jung Bum
AU - Yim, Hyeon Woo
AU - Park, Yong Chon
PY - 2017/9/1
Y1 - 2017/9/1
N2 - Objective The aim of this study was to validate the psychotic depression assessment scale (PDAS), which includes the six-item melancholia subscale from the Hamilton depression rating scale (HAMD-6) and the five-item psychosis subscale from the brief psychiatric rating scale (BPRS-5). Data from the Clinical Research Center for Depression (CRESCEND) study, which is a 52-week naturalistic trial, were analyzed. Methods Fifty-two patients with psychotic depression from the CRESCEND study met our inclusion criteria. The patients underwent the following psychometric assessments: the PDAS, including HAMD-6 and BPRS-5, the clinical global impression scales, the HAMD, the positive symptom subscale, and the negative symptom subscale. Assessments were performed at the baseline and then at weeks 1, 2, 4, 8, 12, 24, and 52. Spearman correlation analyses were used to assess the clinical validity and responsiveness of the PDAS. Results The clinical validity and responsiveness of the PDAS, including HAMD-6 and BPRS-5, were acceptable, with the exception of the clinical responsiveness of the PDAS for positive symptoms and the clinical responsiveness of BPRS-5 for negative symptoms. Conclusion The clinical relevance of the PDAS has been confirmed and this clinical validation will enhance its clinical utility and availability.
AB - Objective The aim of this study was to validate the psychotic depression assessment scale (PDAS), which includes the six-item melancholia subscale from the Hamilton depression rating scale (HAMD-6) and the five-item psychosis subscale from the brief psychiatric rating scale (BPRS-5). Data from the Clinical Research Center for Depression (CRESCEND) study, which is a 52-week naturalistic trial, were analyzed. Methods Fifty-two patients with psychotic depression from the CRESCEND study met our inclusion criteria. The patients underwent the following psychometric assessments: the PDAS, including HAMD-6 and BPRS-5, the clinical global impression scales, the HAMD, the positive symptom subscale, and the negative symptom subscale. Assessments were performed at the baseline and then at weeks 1, 2, 4, 8, 12, 24, and 52. Spearman correlation analyses were used to assess the clinical validity and responsiveness of the PDAS. Results The clinical validity and responsiveness of the PDAS, including HAMD-6 and BPRS-5, were acceptable, with the exception of the clinical responsiveness of the PDAS for positive symptoms and the clinical responsiveness of BPRS-5 for negative symptoms. Conclusion The clinical relevance of the PDAS has been confirmed and this clinical validation will enhance its clinical utility and availability.
KW - 5-item psychosis subscale
KW - 6-item melancholia subscale
KW - Clinical validation
KW - Psychotic depression
KW - Psychotic depression assessment scale
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U2 - 10.4306/pi.2017.14.5.568
DO - 10.4306/pi.2017.14.5.568
M3 - Article
AN - SCOPUS:85029767377
SN - 1738-3684
VL - 14
SP - 568
EP - 576
JO - Psychiatry Investigation
JF - Psychiatry Investigation
IS - 5
ER -