Coffee intake and obesity: A meta-analysis

Ariel Lee, Woobin Lim, Seoyeon Kim, Hayeong Khil, Eugene Cheon, Soobin An, Sungeun Hong, Dong Hoon Lee, Seok Seong Kang, Hannah Oh, Nana Keum, Chung Cheng Hsieh

Research output: Contribution to journalReview articlepeer-review

54 Citations (Scopus)


Many studies have explored the relationship between coffee—one of the most commonly consumed beverages today—and obesity. Despite inconsistent results, the relationship has not been systematically summarized. Thus, we conducted a meta-analysis by compiling data from 12 epidemiologic studies identified from PubMed and Embase through February 2019. The included studies assessed obesity by body mass index (BMI, a measure of overall adiposity) or waist circumference (WC, a measure of central adiposity); analyzed the measure as a continuous outcome or binary outcome. Using random effects model, weighted mean difference (WMD) and 95% confidence interval (CI) were obtained for continuous outcomes; summary relative risk (RR) and 95% CI for the highest vs. lowest categories of coffee intake were estimated for binary outcome. For BMI, WMD was −0.08 (95% CI −0.14, −0.02); RR was 1.49 (95% CI 0.97, 2.29). For WC, WMD was −0.27 (95% CI −0.51, −0.02) and RR was 1.07 (95% CI 0.84, 1.36). In subgroup analysis by sex, evidence for an inverse association was more evident in men, specifically for continuous outcome, with WMD −0.05 (95% CI −0.09, −0.02) for BMI and −0.21 (95% CI −0.35, −0.08) for WC. Our meta-analysis suggests that higher coffee intake might be modestly associated with reduced adiposity, particularly in men.

Original languageEnglish
Article number1274
Issue number6
Publication statusPublished - 2019 Jun

Bibliographical note

Funding Information:
Funding: This work was supported by the National Research Foundation of Korea (NRF) grants funded by the Korea government (2018R1C1B6008822 [N.K.]; 2018R1A4A1022589 [N.K.]; 2019R1G1A1004227 [H.O.]); a Korea University Grant (K1808781) (H.O.); the Dongguk University Research Grant of 2017 (N.K.).

Publisher Copyright:
© 2019, MDPI AG. All rights reserved.


  • Adiposity
  • Body mass index
  • Coffee intake
  • Meta-analysis
  • Obesity
  • Waist circumference

ASJC Scopus subject areas

  • Food Science
  • Nutrition and Dietetics


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