TY - JOUR
T1 - Cognitive stimulation as a therapeutic modality for dementia
T2 - A meta-analysis
AU - Kim, Kayoung
AU - Han, Ji Won
AU - So, Yoonseop
AU - Seo, Jiyeong
AU - Kim, You Joung
AU - Park, Joon Hyuk
AU - Lee, Seok Bum
AU - Lee, Jung Jae
AU - Jeong, Hyun Ghang
AU - Kim, Tae Hui
AU - Kim, Ki Woong
N1 - Funding Information:
This study was supported by grants from the Korean Health Technology R&D Project, Ministry for Health, Welfare, and Family Affairs, Republic of Korea [grant number HI09C1379 (A092077)] and from the Korean Health Technology R&D Project, Ministry of Health and Welfare, Republic of Korea (grant number HI12C2018).
Publisher Copyright:
© 2017 Korean Neuropsychiatric Association.
PY - 2017/9
Y1 - 2017/9
N2 - Objective Although cognitive stimulation (CS) is one of the most popular non-pharmacological interventions for people with dementia, its efficacy is still debatable. We performed a meta-analysis of randomized controlled trials (RCTs) on the efficacy of CS in people with dementia. Methods Data sources were identified by searching PubMed, MEDLINE, Embase, psychINFO, and Cochrane Reviews Library. A total of 7,354 articles were identified, and of these, 30 RCTs were selected based on the selection criteria. Of these 30 RCTs, 14 were finally included in our meta-analysis [731 participants with dementia; 412 received CS (CS group) and 319 received usual care (control group)]. Results We found that the people with dementia had a moderate benefit from CS. The mean difference between the CS and control groups was 2.21 [95% CI (0.93, 3.49), Z=3.38, p=0.00007] in the Alzheimer’s Disease Assessment Scale-Cognition and 1.41 [95% CI (0.98, 1.84), Z=6.39, p<0.00001] in the Mini-Mental State Examination. CS also improved quality of life in people with dementia [95% CI (0.72, 3.38), Z=3.02, p=0.003]. Conclusion CS is effective for improving cognition and quality of life in people with dementia; however, its effects were small to moderate.
AB - Objective Although cognitive stimulation (CS) is one of the most popular non-pharmacological interventions for people with dementia, its efficacy is still debatable. We performed a meta-analysis of randomized controlled trials (RCTs) on the efficacy of CS in people with dementia. Methods Data sources were identified by searching PubMed, MEDLINE, Embase, psychINFO, and Cochrane Reviews Library. A total of 7,354 articles were identified, and of these, 30 RCTs were selected based on the selection criteria. Of these 30 RCTs, 14 were finally included in our meta-analysis [731 participants with dementia; 412 received CS (CS group) and 319 received usual care (control group)]. Results We found that the people with dementia had a moderate benefit from CS. The mean difference between the CS and control groups was 2.21 [95% CI (0.93, 3.49), Z=3.38, p=0.00007] in the Alzheimer’s Disease Assessment Scale-Cognition and 1.41 [95% CI (0.98, 1.84), Z=6.39, p<0.00001] in the Mini-Mental State Examination. CS also improved quality of life in people with dementia [95% CI (0.72, 3.38), Z=3.02, p=0.003]. Conclusion CS is effective for improving cognition and quality of life in people with dementia; however, its effects were small to moderate.
KW - Cognition
KW - Cognitive stimulation
KW - Dementia
KW - Meta-analysis
KW - Quality of life
UR - http://www.scopus.com/inward/record.url?scp=85029772050&partnerID=8YFLogxK
U2 - 10.4306/pi.2017.14.5.626
DO - 10.4306/pi.2017.14.5.626
M3 - Article
AN - SCOPUS:85029772050
SN - 1738-3684
VL - 14
SP - 626
EP - 639
JO - Psychiatry Investigation
JF - Psychiatry Investigation
IS - 5
ER -
