Abstract
Red gold/blue gold: A highly convenient colorimetric method for the identification of single-nucleotide polymorphism was developed by utilizing gold nanoparticles and an allele-specific polymerase chain reaction. Its diagnostic capability was successfully demonstrated by correctly identifying various mutations in the BRCA1 gene.
Original language | English |
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Pages (from-to) | 1387-1390 |
Number of pages | 4 |
Journal | ChemBioChem |
Volume | 12 |
Issue number | 9 |
DOIs | |
Publication status | Published - 2011 Jun 14 |
Externally published | Yes |
Keywords
- BRCA
- Gold
- Nanoparticles
- Polymerase chain reaction
- Single nucleotide polymorphism
- Thiolated primer
ASJC Scopus subject areas
- Biochemistry
- Molecular Medicine
- Molecular Biology
- Organic Chemistry