Colorimetric SNP Genotyping Based on Allele-Specific PCR by Using a Thiol-Labeled Primer

Ye Lim Jung; Cheulhee Jung; Harshala Parab; Dae Yeon Cho; Hyun Gyu Park

doi:10.1002/cbic.201100098

Colorimetric SNP Genotyping Based on Allele-Specific PCR by Using a Thiol-Labeled Primer

Ye Lim Jung, Cheulhee Jung, Harshala Parab, Dae Yeon Cho, Hyun Gyu Park

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

Red gold/blue gold: A highly convenient colorimetric method for the identification of single-nucleotide polymorphism was developed by utilizing gold nanoparticles and an allele-specific polymerase chain reaction. Its diagnostic capability was successfully demonstrated by correctly identifying various mutations in the BRCA1 gene.

Original language	English
Pages (from-to)	1387-1390
Number of pages	4
Journal	ChemBioChem
Volume	12
Issue number	9
DOIs	https://doi.org/10.1002/cbic.201100098
Publication status	Published - 2011 Jun 14
Externally published	Yes

Keywords

BRCA
Gold
Nanoparticles
Polymerase chain reaction
Single nucleotide polymorphism
Thiolated primer

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Organic Chemistry

Access to Document

10.1002/cbic.201100098

Cite this

@article{4e90b52927364d08bfdbd9459770372c,

title = "Colorimetric SNP Genotyping Based on Allele-Specific PCR by Using a Thiol-Labeled Primer",

abstract = "Red gold/blue gold: A highly convenient colorimetric method for the identification of single-nucleotide polymorphism was developed by utilizing gold nanoparticles and an allele-specific polymerase chain reaction. Its diagnostic capability was successfully demonstrated by correctly identifying various mutations in the BRCA1 gene.",

keywords = "BRCA, Gold, Nanoparticles, Polymerase chain reaction, Single nucleotide polymorphism, Thiolated primer",

author = "Jung, {Ye Lim} and Cheulhee Jung and Harshala Parab and Cho, {Dae Yeon} and Park, {Hyun Gyu}",

year = "2011",

month = jun,

day = "14",

doi = "10.1002/cbic.201100098",

language = "English",

volume = "12",

pages = "1387--1390",

journal = "ChemBioChem",

issn = "1439-4227",

publisher = "John Wiley and Sons Inc.",

number = "9",

}

TY - JOUR

T1 - Colorimetric SNP Genotyping Based on Allele-Specific PCR by Using a Thiol-Labeled Primer

AU - Jung, Ye Lim

AU - Jung, Cheulhee

AU - Parab, Harshala

AU - Cho, Dae Yeon

AU - Park, Hyun Gyu

PY - 2011/6/14

Y1 - 2011/6/14

N2 - Red gold/blue gold: A highly convenient colorimetric method for the identification of single-nucleotide polymorphism was developed by utilizing gold nanoparticles and an allele-specific polymerase chain reaction. Its diagnostic capability was successfully demonstrated by correctly identifying various mutations in the BRCA1 gene.

AB - Red gold/blue gold: A highly convenient colorimetric method for the identification of single-nucleotide polymorphism was developed by utilizing gold nanoparticles and an allele-specific polymerase chain reaction. Its diagnostic capability was successfully demonstrated by correctly identifying various mutations in the BRCA1 gene.

KW - BRCA

KW - Gold

KW - Nanoparticles

KW - Polymerase chain reaction

KW - Single nucleotide polymorphism

KW - Thiolated primer

UR - http://www.scopus.com/inward/record.url?scp=79958715238&partnerID=8YFLogxK

U2 - 10.1002/cbic.201100098

DO - 10.1002/cbic.201100098

M3 - Article

C2 - 21557428

AN - SCOPUS:79958715238

SN - 1439-4227

VL - 12

SP - 1387

EP - 1390

JO - ChemBioChem

JF - ChemBioChem

IS - 9

ER -

Colorimetric SNP Genotyping Based on Allele-Specific PCR by Using a Thiol-Labeled Primer

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this