Keyphrases
Pharmacokinetics
100%
Genetic Polymorphism
100%
Pharmacodynamics
100%
Haloperidol
100%
Itraconazole
100%
CYP2D6*10
100%
Genotype
81%
Cytochrome P450 2D6 (CYP2D6)
54%
Placebo
45%
Time-concentration Curve
27%
Statistical Significance
18%
Rating Scales
18%
Akathisia
18%
Oral Clearance
18%
Adverse Events
9%
Nineteen
9%
Healthy Volunteers
9%
Pharmacodynamic Interactions
9%
Cytochrome P450 3A4 (CYP3A4)
9%
Moderating Effect
9%
Mean Area
9%
Randomized Crossover
9%
QT Prolongation
9%
CYP2D6 Genotype
9%
Neurological Effects
9%
CYP3A4 Inhibition
9%
Wild Genotype
9%
Pharmacology, Toxicology and Pharmaceutical Science
Normal Human
100%
Pharmacodynamics
100%
4 (para chlorophenyl) 1 [3 (para fluorobenzoyl)propyl] 4 piperidinol
100%
CYP2D6
100%
Itraconazole
100%
Pharmacokinetics
100%
Placebo
27%
Side Effect
11%
CYP3A4
11%
Akathisia
11%
Adverse Event
5%
Neuroscience
Genetic Polymorphism
100%
Cytochrome P450 2D6
100%
Itraconazole
100%
Pharmacokinetics
100%
Haloperidol
100%
Placebo
27%
Akathisia
11%
Cytochrome P450 3A4
11%
Immunology and Microbiology
Normal Human
100%
Pharmacokinetics
100%
Genetic Polymorphism
100%
Pharmacodynamics
100%
Oral Clearance
40%