TY - GEN
T1 - Common-path Fourier-domain optical coherence tomography in ophthalmology applications
AU - Han, Jae Ho
AU - Liu, Xuan
AU - Zhang, Kang
AU - Kang, Jin U.
PY - 2009
Y1 - 2009
N2 - We have demonstrated in vivo three-dimensional imaging and estimated localized and quantitative hemoglobin oxygen saturation (SO2) of blood vessel by using a simple, easy to operate common-path Fourier-domain optical coherence tomography (OCT) system. The common-path OCT system can be easily integrated with various surgical tools and we demonstrated its usefulness by imaging outer and inner intraocular tissues such as cornea and neurosensory retinal layers as well as detecting SO2 level from a chicken embryo. The system uses 800nm near infrared broadband light sources and has axial resolution as low as 3μm in air. Self-adaptive scanning mechanism with real-time surface recognition and feedback control was also applied to the probe where the scanning probe tracks the sample surface variance and effective imaging depth was largely extended to the probe's free-moving range.
AB - We have demonstrated in vivo three-dimensional imaging and estimated localized and quantitative hemoglobin oxygen saturation (SO2) of blood vessel by using a simple, easy to operate common-path Fourier-domain optical coherence tomography (OCT) system. The common-path OCT system can be easily integrated with various surgical tools and we demonstrated its usefulness by imaging outer and inner intraocular tissues such as cornea and neurosensory retinal layers as well as detecting SO2 level from a chicken embryo. The system uses 800nm near infrared broadband light sources and has axial resolution as low as 3μm in air. Self-adaptive scanning mechanism with real-time surface recognition and feedback control was also applied to the probe where the scanning probe tracks the sample surface variance and effective imaging depth was largely extended to the probe's free-moving range.
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U2 - 10.1109/LISSA.2009.4906735
DO - 10.1109/LISSA.2009.4906735
M3 - Conference contribution
AN - SCOPUS:67650657202
SN - 9781424442935
T3 - 2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009
SP - 163
EP - 166
BT - 2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009
T2 - 2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009
Y2 - 9 April 2009 through 10 April 2009
ER -