Comparison of characteristics and survival between prospective and retrospective Korea human immunodeficiency virus/Acquired immune deficiency syndrome cohort studies

Jun Hyoung Kim; Yunsu Choi; Joon Young Song; Shin Woo Kim; Sang Il Kim; Mee Kyung Kee; Bo Youl Choi; Jun Yong Choi

doi:10.3947/ic.2019.51.4.393

Comparison of characteristics and survival between prospective and retrospective Korea human immunodeficiency virus/Acquired immune deficiency syndrome cohort studies

Jun Hyoung Kim, Yunsu Choi, Joon Young Song, Shin Woo Kim, Sang Il Kim, Mee Kyung Kee, Bo Youl Choi, Jun Yong Choi

Research output: Contribution to journal › Article › peer-review

Abstract

By comparing the data of prospectively and retrospectively enrolled cohorts, we evaluated whether the prospective cohort represented all patients in the retrospective cohort. The prospectively enrolled subjects were older and had lower CD4+ T cell counts, higher viral load. In addition, the initial antiretroviral treatment regimen of the prospective cohort consisted of less integrase strand transfer inhibitor-containing regimens. The 20-year survival rate was 51.8% in the prospective cohort and 84.6% in the retrospective cohort, respectively (P = 0.844). This study suggests the prospective cohort study may not represent all patients.

Original language	English
Pages (from-to)	393-398
Number of pages	6
Journal	Infection and Chemotherapy
Volume	51
Issue number	4
DOIs	https://doi.org/10.3947/ic.2019.51.4.393
Publication status	Published - 2019 Dec 1

Keywords

Cohort study
HIV/AIDS
Survival rates

ASJC Scopus subject areas

Infectious Diseases
Pharmacology (medical)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3947/ic.2019.51.4.393

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abstract = "By comparing the data of prospectively and retrospectively enrolled cohorts, we evaluated whether the prospective cohort represented all patients in the retrospective cohort. The prospectively enrolled subjects were older and had lower CD4+ T cell counts, higher viral load. In addition, the initial antiretroviral treatment regimen of the prospective cohort consisted of less integrase strand transfer inhibitor-containing regimens. The 20-year survival rate was 51.8% in the prospective cohort and 84.6% in the retrospective cohort, respectively (P = 0.844). This study suggests the prospective cohort study may not represent all patients.",

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T1 - Comparison of characteristics and survival between prospective and retrospective Korea human immunodeficiency virus/Acquired immune deficiency syndrome cohort studies

AU - Kim, Jun Hyoung

AU - Choi, Yunsu

AU - Song, Joon Young

AU - Kim, Shin Woo

AU - Kim, Sang Il

AU - Kee, Mee Kyung

AU - Choi, Bo Youl

AU - Choi, Jun Yong

PY - 2019/12/1

Y1 - 2019/12/1

N2 - By comparing the data of prospectively and retrospectively enrolled cohorts, we evaluated whether the prospective cohort represented all patients in the retrospective cohort. The prospectively enrolled subjects were older and had lower CD4+ T cell counts, higher viral load. In addition, the initial antiretroviral treatment regimen of the prospective cohort consisted of less integrase strand transfer inhibitor-containing regimens. The 20-year survival rate was 51.8% in the prospective cohort and 84.6% in the retrospective cohort, respectively (P = 0.844). This study suggests the prospective cohort study may not represent all patients.

AB - By comparing the data of prospectively and retrospectively enrolled cohorts, we evaluated whether the prospective cohort represented all patients in the retrospective cohort. The prospectively enrolled subjects were older and had lower CD4+ T cell counts, higher viral load. In addition, the initial antiretroviral treatment regimen of the prospective cohort consisted of less integrase strand transfer inhibitor-containing regimens. The 20-year survival rate was 51.8% in the prospective cohort and 84.6% in the retrospective cohort, respectively (P = 0.844). This study suggests the prospective cohort study may not represent all patients.

KW - Cohort study

KW - HIV/AIDS

KW - Survival rates

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Comparison of characteristics and survival between prospective and retrospective Korea human immunodeficiency virus/Acquired immune deficiency syndrome cohort studies

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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