Comparison of sporadic sclerotic fibroma and solitary fibrous tumor in the oral cavity

Ju Han Lee, Jung Suk An, Eung Seok Lee, Soon Young Kwon, Young Sik Kim

    Research output: Contribution to journalArticlepeer-review

    7 Citations (Scopus)

    Abstract

    Sporadic sclerotic fibroma (SF) and solitary fibrous tumor (SFT) arising in the oral cavity are very rate. In this report, we describe two cases of oral pathology, one involving SF and the other involving SFT. Both cases presented with well-circumscribed, firm nodules with similar gross findings. However, the histologic findings of the SF and SFT showed rather distinct features. The SF was composed of hyalinized sclerotic collagen bundles arranged in a whorled pattern, whereas the SFT was formed by spindles cells arranged in hypo- and hypercellular areas. The immunohistochemical findings were similar in both cases; there was positivity for vimentin, CD34, and CD99, but bcl-2 positivity was only seen in the SFT. Although their histopathologies are similar, SF and SFT should be considered in the differential diagnosis of soft tissue tumors in the oral cavity.

    Original languageEnglish
    Pages (from-to)535-539
    Number of pages5
    JournalYonsei medical journal
    Volume48
    Issue number3
    DOIs
    Publication statusPublished - 2007 Jun

    Keywords

    • Bcl-2
    • Oral cavity
    • Sclerotic fibroma
    • Solitary fibrous tumor

    ASJC Scopus subject areas

    • General Medicine

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