Complete nucleotide sequence of a mumps virus genotype I strain isolated in Korea

Joo Yeon Lee, Byoung Kuk Na, Ho Dong Lee, Sung Wook Chang, Kyung Ae Kim, Jee Hee Kim, Hae Wol Cho, Joon Kim, Chun Kang

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


The complete nucleotide sequence of mumps virus isolated in Korea, Dg1062/Korea/98 (Dg1062), was determined. As other mumps viruses, its genome was to be 15,384 nucleotides (nts) in length and encoded seven proteins. The both 5′ and 3′ ends were confirmed to be 55 and 24 nts by RACE method, respectively. The full-length nucleotide sequence of Dg1062 isolate differed from other strains by 2.9-6.8% in the nucleotide sequence level, resulting in 206 nucleotide and 54 amino acid substitutions which were observed in only Dg1062 isolate relative to the consensus sequences of other strains. Despite the variations of amino acids over the full genome including HN gene, it might be considered that this isolate have no significant variations in the antigenic sites. This result is the first report of full-length genome of genotype I strain and provides an overview on the diversity of genetic characteristics of circulating mumps virus.

Original languageEnglish
Pages (from-to)201-205
Number of pages5
JournalVirus Genes
Issue number2
Publication statusPublished - 2004 Mar


  • Complete nucleotide sequence
  • Genotype I
  • Mumps virus

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Virology


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