Construction of an immunotoxin via site-specific conjugation of anti-Her2 IgG and engineered Pseudomonas exotoxin A

Pharmacology, Toxicology and Pharmaceutical Science

• Immunoglobulin G 100%
• Gamma Urogastrone 100%
• Epidermal Growth Factor Receptor 2 100%
• Immunotoxin 100%
• Pseudomonas Exotoxin 100%
• Trastuzumab 50%
• Amino Acid 33%
• Malignant Neoplasm 33%
• Cysteine 33%
• Cytotoxicity 16%
• Tumor Regression 16%
• Infectious Agent 16%
• Fusion Protein 16%
• Elongation Factor 2 16%
• Cell Protein 16%
• Maleimide 16%
• Immunoglobulin 16%
• Immunogenicity 16%

Keyphrases

• Anti-human Epidermal Growth Factor Receptor 2 100%
• Fragment Crystallizable 33%
• Dibenzocyclooctadiene 16%
• Antibody-mediated Immune Response 16%
• Full-length Antibodies 16%
• Toxic Fragments 16%
• Unpaired Cysteine 16%

Immunology and Microbiology

• Fragment Crystallizable Receptor 16%