Construction of neonatal diffusion atlases via spatio-angular consistency

Behrouz Saghafi, Geng Chen, Feng Shi, Pew Thian Yap, Dinggang Shen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

Atlases constructed using diffusion-weighted imaging (DWI) are important tools for studying human brain development. Atlas construction is in general a two-step process involving image registration and image fusion. The focus of most studies so far has been on improving registration thus image fusion is commonly performed using simple averaging, often resulting in fuzzy atlases. In this paper, we propose a patch-based method for DWI atlas construction. Unlike other atlases that are based on the diffusion tensor model, our atlas is model-free. Instead of generating an atlas for each gradient direction independently and hence neglecting inter-image correlation, we propose to construct the atlas by jointly considering diffusion-weighted images of neighboring gradient directions. We employ a group regularization framework where local patches of angularly neighboring images are constrained for consistent spatio-angular atlas reconstruction. Experimental results verify that our atlas, constructed for neonatal data, reveals more structural details compared with the average atlas especially in the cortical regions. Our atlas also yields greater accuracy when used for image normalization.

Original languageEnglish
Title of host publicationPatch-Based Techniques in Medical Imaging - 2nd International Workshop, Patch-MI 2016 held in conjunction with MICCAI 2016, Proceedings
EditorsPierrick Coupe, Brent C. Munsell, Daniel Rueckert, Yiqiang Zhan, Guorong Wu
PublisherSpringer Verlag
Pages9-16
Number of pages8
ISBN (Print)9783319471174
DOIs
Publication statusPublished - 2016
Event2nd International Workshop on Patch-Based Techniques in Medical Imaging, Patch-MI 2016 held in conjunction with 19th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2016 - Athens, Greece
Duration: 2016 Oct 172016 Oct 17

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume9993 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Other

Other2nd International Workshop on Patch-Based Techniques in Medical Imaging, Patch-MI 2016 held in conjunction with 19th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2016
Country/TerritoryGreece
CityAthens
Period16/10/1716/10/17

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

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