Contamination of polychlorinated biphenyls and organochlorine pesticides in breast milk in Korea: Time-course variation, influencing factors, and exposure assessment

Sunggyu Lee; Sunmi Kim; Hyun Kyung Lee; In Seok Lee; Jeongim Park; Hai Joong Kim; Jeong Jae Lee; Gyuyeon Choi; Sooran Choi; Sungjoo Kim; Su Young Kim; Kyungho Choi; Sungkyoon Kim; Hyo Bang Moon

doi:10.1016/j.chemosphere.2013.08.011

Contamination of polychlorinated biphenyls and organochlorine pesticides in breast milk in Korea: Time-course variation, influencing factors, and exposure assessment

Sunggyu Lee, Sunmi Kim, Hyun Kyung Lee, In Seok Lee, Jeongim Park, Hai Joong Kim, Jeong Jae Lee, Gyuyeon Choi, Sooran Choi, Sungjoo Kim, Su Young Kim, Kyungho Choi, Sungkyoon Kim, Hyo Bang Moon

Research output: Contribution to journal › Article › peer-review

40 Citations (Scopus)

Abstract

Breast milk is a noninvasive specimen to assess maternal and infant exposure to polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs). In this study, 206 breast milk samples were collected from 87 participants during lactation, at <7, 15, 30, or 90days postpartum in four cities in Korea. The total concentrations of PCBs (σPCB) and OCPs (σOCP) ranged from <LOQ to 84.0 (median: 12.1) ngg^-1 lipid weight and from <LOQ to 559 (median: 144) ngg^-1 lipid weight, respectively. The residue levels of these contaminants measured in our study were relatively lower than those reported for European, African and Asian populations. Within a month postpartum typically after day seven the levels of σPCB and σOCP significantly increased. Some OCP compounds were correlated with maternal age, BMI, parity, and delivery mode. Certain types of dietary habits such as seafood and noodle consumption were significantly associated with σPCB and σOCP. The estimated daily intakes (EDIs) of σPCB and σOCP were 45.2-127ngkg^-1bwday^-1 and 625-1259ngkg^-1bwday^-1 during lactation, respectively, which are lower than the threshold values proposed by the US EPA and Health Canada. The exposure of Korean infants to chlordanes via breast milk had a potential health risk which deserves further investigation.

Original language	English
Pages (from-to)	1578-1585
Number of pages	8
Journal	Chemosphere
Volume	93
Issue number	8
DOIs	https://doi.org/10.1016/j.chemosphere.2013.08.011
Publication status	Published - 2013 Nov
Externally published	Yes

Bibliographical note

Funding Information:
We would like to express our gratitude to all participating mothers for their great efforts in collecting breast milk samples. This study was supported by a Grant from the Korea Food & Drug Administration (KFDA, 11162KFDA722).

Keywords

Chlordane
Estimated daily intake
Health risk
Lactation
Threshold value

ASJC Scopus subject areas

Environmental Engineering
Environmental Chemistry
General Chemistry
Pollution
Public Health, Environmental and Occupational Health
Health, Toxicology and Mutagenesis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.chemosphere.2013.08.011

Cite this

Lee, S., Kim, S., Lee, H. K., Lee, I. S., Park, J., Kim, H. J., Lee, J. J., Choi, G., Choi, S., Kim, S., Kim, S. Y., Choi, K., Kim, S., & Moon, H. B. (2013). Contamination of polychlorinated biphenyls and organochlorine pesticides in breast milk in Korea: Time-course variation, influencing factors, and exposure assessment. Chemosphere, 93(8), 1578-1585. https://doi.org/10.1016/j.chemosphere.2013.08.011

Lee, S, Kim, S, Lee, HK, Lee, IS, Park, J, Kim, HJ, Lee, JJ, Choi, G, Choi, S, Kim, S, Kim, SY, Choi, K, Kim, S & Moon, HB 2013, 'Contamination of polychlorinated biphenyls and organochlorine pesticides in breast milk in Korea: Time-course variation, influencing factors, and exposure assessment', Chemosphere, vol. 93, no. 8, pp. 1578-1585. https://doi.org/10.1016/j.chemosphere.2013.08.011

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abstract = "Breast milk is a noninvasive specimen to assess maternal and infant exposure to polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs). In this study, 206 breast milk samples were collected from 87 participants during lactation, at <7, 15, 30, or 90days postpartum in four cities in Korea. The total concentrations of PCBs (σPCB) and OCPs (σOCP) ranged from -1 lipid weight and from -1 lipid weight, respectively. The residue levels of these contaminants measured in our study were relatively lower than those reported for European, African and Asian populations. Within a month postpartum typically after day seven the levels of σPCB and σOCP significantly increased. Some OCP compounds were correlated with maternal age, BMI, parity, and delivery mode. Certain types of dietary habits such as seafood and noodle consumption were significantly associated with σPCB and σOCP. The estimated daily intakes (EDIs) of σPCB and σOCP were 45.2-127ngkg-1bwday-1 and 625-1259ngkg-1bwday-1 during lactation, respectively, which are lower than the threshold values proposed by the US EPA and Health Canada. The exposure of Korean infants to chlordanes via breast milk had a potential health risk which deserves further investigation.",

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author = "Sunggyu Lee and Sunmi Kim and Lee, {Hyun Kyung} and Lee, {In Seok} and Jeongim Park and Kim, {Hai Joong} and Lee, {Jeong Jae} and Gyuyeon Choi and Sooran Choi and Sungjoo Kim and Kim, {Su Young} and Kyungho Choi and Sungkyoon Kim and Moon, {Hyo Bang}",

note = "Funding Information: We would like to express our gratitude to all participating mothers for their great efforts in collecting breast milk samples. This study was supported by a Grant from the Korea Food & Drug Administration (KFDA, 11162KFDA722). ",

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AU - Lee, Hyun Kyung

AU - Lee, In Seok

AU - Park, Jeongim

AU - Kim, Hai Joong

AU - Lee, Jeong Jae

AU - Choi, Gyuyeon

AU - Choi, Sooran

AU - Kim, Sungjoo

AU - Kim, Su Young

AU - Choi, Kyungho

AU - Kim, Sungkyoon

AU - Moon, Hyo Bang

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N2 - Breast milk is a noninvasive specimen to assess maternal and infant exposure to polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs). In this study, 206 breast milk samples were collected from 87 participants during lactation, at <7, 15, 30, or 90days postpartum in four cities in Korea. The total concentrations of PCBs (σPCB) and OCPs (σOCP) ranged from -1 lipid weight and from -1 lipid weight, respectively. The residue levels of these contaminants measured in our study were relatively lower than those reported for European, African and Asian populations. Within a month postpartum typically after day seven the levels of σPCB and σOCP significantly increased. Some OCP compounds were correlated with maternal age, BMI, parity, and delivery mode. Certain types of dietary habits such as seafood and noodle consumption were significantly associated with σPCB and σOCP. The estimated daily intakes (EDIs) of σPCB and σOCP were 45.2-127ngkg-1bwday-1 and 625-1259ngkg-1bwday-1 during lactation, respectively, which are lower than the threshold values proposed by the US EPA and Health Canada. The exposure of Korean infants to chlordanes via breast milk had a potential health risk which deserves further investigation.

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Contamination of polychlorinated biphenyls and organochlorine pesticides in breast milk in Korea: Time-course variation, influencing factors, and exposure assessment

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

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