Control of tandem isomerizations: Flow-assisted reactions of: O -lithiated aryl benzyl ethers

Hyune Jea Lee, Heejin Kim, Jun Ichi Yoshida, Dong Pyo Kim

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)


Tandem chemical changes are often difficult to control at will, because they proceed rapidly through multiple unstable reactive intermediates. It is desirable to develop a novel method for controlling such tandem changes to obtain desired products with high selectivity. Herein, we report a flow microreactor platform for controlling tandem isomerizations of o-lithiated aryl benzyl ethers based on precise residence time control.

Original languageEnglish
Pages (from-to)547-550
Number of pages4
JournalChemical Communications
Issue number5
Publication statusPublished - 2018
Externally publishedYes

Bibliographical note

Funding Information:
We acknowledge the National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIP) (No. 2017R1A3B1023598). This work was also supported by a Grant in-Aid for Scientific Research (S) 26220804 and a Grant-in-Aid for Young Scientists (B) 16K17898 funded by the Japan Society for the Promotion of Science (JSPS).

Publisher Copyright:
© 2018 The Royal Society of Chemistry.

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry


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