Control of tandem isomerizations: Flow-assisted reactions of: O -lithiated aryl benzyl ethers

Hyune Jea Lee; Heejin Kim; Jun Ichi Yoshida; Dong Pyo Kim

doi:10.1039/c7cc08460a

Control of tandem isomerizations: Flow-assisted reactions of: O -lithiated aryl benzyl ethers

Hyune Jea Lee, Heejin Kim, Jun Ichi Yoshida, Dong Pyo Kim

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

Tandem chemical changes are often difficult to control at will, because they proceed rapidly through multiple unstable reactive intermediates. It is desirable to develop a novel method for controlling such tandem changes to obtain desired products with high selectivity. Herein, we report a flow microreactor platform for controlling tandem isomerizations of o-lithiated aryl benzyl ethers based on precise residence time control.

Original language	English
Pages (from-to)	547-550
Number of pages	4
Journal	Chemical Communications
Volume	54
Issue number	5
DOIs	https://doi.org/10.1039/c7cc08460a
Publication status	Published - 2018
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c7cc08460a

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title = "Control of tandem isomerizations: Flow-assisted reactions of: O -lithiated aryl benzyl ethers",

abstract = "Tandem chemical changes are often difficult to control at will, because they proceed rapidly through multiple unstable reactive intermediates. It is desirable to develop a novel method for controlling such tandem changes to obtain desired products with high selectivity. Herein, we report a flow microreactor platform for controlling tandem isomerizations of o-lithiated aryl benzyl ethers based on precise residence time control.",

author = "Lee, {Hyune Jea} and Heejin Kim and Yoshida, {Jun Ichi} and Kim, {Dong Pyo}",

note = "Funding Information: We acknowledge the National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIP) (No. 2017R1A3B1023598). This work was also supported by a Grant in-Aid for Scientific Research (S) 26220804 and a Grant-in-Aid for Young Scientists (B) 16K17898 funded by the Japan Society for the Promotion of Science (JSPS). Publisher Copyright: {\textcopyright} 2018 The Royal Society of Chemistry.",

year = "2018",

doi = "10.1039/c7cc08460a",

language = "English",

volume = "54",

pages = "547--550",

journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - Control of tandem isomerizations

T2 - Flow-assisted reactions of: O -lithiated aryl benzyl ethers

AU - Lee, Hyune Jea

AU - Kim, Heejin

AU - Yoshida, Jun Ichi

AU - Kim, Dong Pyo

N1 - Funding Information: We acknowledge the National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIP) (No. 2017R1A3B1023598). This work was also supported by a Grant in-Aid for Scientific Research (S) 26220804 and a Grant-in-Aid for Young Scientists (B) 16K17898 funded by the Japan Society for the Promotion of Science (JSPS). Publisher Copyright: © 2018 The Royal Society of Chemistry.

PY - 2018

Y1 - 2018

N2 - Tandem chemical changes are often difficult to control at will, because they proceed rapidly through multiple unstable reactive intermediates. It is desirable to develop a novel method for controlling such tandem changes to obtain desired products with high selectivity. Herein, we report a flow microreactor platform for controlling tandem isomerizations of o-lithiated aryl benzyl ethers based on precise residence time control.

AB - Tandem chemical changes are often difficult to control at will, because they proceed rapidly through multiple unstable reactive intermediates. It is desirable to develop a novel method for controlling such tandem changes to obtain desired products with high selectivity. Herein, we report a flow microreactor platform for controlling tandem isomerizations of o-lithiated aryl benzyl ethers based on precise residence time control.

UR - http://www.scopus.com/inward/record.url?scp=85040626350&partnerID=8YFLogxK

U2 - 10.1039/c7cc08460a

DO - 10.1039/c7cc08460a

M3 - Article

C2 - 29292444

AN - SCOPUS:85040626350

SN - 1359-7345

VL - 54

SP - 547

EP - 550

JO - Chemical Communications

JF - Chemical Communications

IS - 5

ER -

Control of tandem isomerizations: Flow-assisted reactions of: O -lithiated aryl benzyl ethers

Abstract

ASJC Scopus subject areas

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