Convertible organic nanoparticles for near-infrared photothermal ablation of cancer cells

Jaemoon Yang; Jihye Choi; Doyeon Bang; Eunjung Kim; Eun Kyung Lim; Huiyul Park; Jin Suck Suh; Kwangyeol Lee; Kyung Hwa Yoo; Eun Kyung Kim; Yong Min Huh; Seungjoo Haam

doi:10.1002/anie.201005075

Convertible organic nanoparticles for near-infrared photothermal ablation of cancer cells

Jaemoon Yang, Jihye Choi, Doyeon Bang, Eunjung Kim, Eun Kyung Lim, Huiyul Park, Jin Suck Suh, Kwangyeol Lee, Kyung Hwa Yoo, Eun Kyung Kim, Yong Min Huh, Seungjoo Haam

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

440 Citations (Scopus)

Abstract

Infiltrate and destroy: In an environment rich in protonating or oxidative species, such as the intracellular milieu of cancer cells, the main absorption band of spherical, water-soluble polyaniline nanoparticles was red-shifted to a near-infrared (NIR) wavelength as a result of the formation of the emeraldine salt (see picture). The doped nanoparticles caused photothermal ablation of cancer cells upon NIR laser irradiation in vitro and in vivo.

Original language	English
Pages (from-to)	441-444
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	50
Issue number	2
DOIs	https://doi.org/10.1002/anie.201005075
Publication status	Published - 2011 Jan 10

Keywords

cancer
nanoparticles
near-infrared light
photothermal agents
polymers

ASJC Scopus subject areas

Catalysis
Chemistry(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/anie.201005075

Cite this

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title = "Convertible organic nanoparticles for near-infrared photothermal ablation of cancer cells",

abstract = "Infiltrate and destroy: In an environment rich in protonating or oxidative species, such as the intracellular milieu of cancer cells, the main absorption band of spherical, water-soluble polyaniline nanoparticles was red-shifted to a near-infrared (NIR) wavelength as a result of the formation of the emeraldine salt (see picture). The doped nanoparticles caused photothermal ablation of cancer cells upon NIR laser irradiation in vitro and in vivo.",

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T1 - Convertible organic nanoparticles for near-infrared photothermal ablation of cancer cells

AU - Yang, Jaemoon

AU - Choi, Jihye

AU - Bang, Doyeon

AU - Kim, Eunjung

AU - Lim, Eun Kyung

AU - Park, Huiyul

AU - Suh, Jin Suck

AU - Lee, Kwangyeol

AU - Yoo, Kyung Hwa

AU - Kim, Eun Kyung

AU - Huh, Yong Min

AU - Haam, Seungjoo

PY - 2011/1/10

Y1 - 2011/1/10

N2 - Infiltrate and destroy: In an environment rich in protonating or oxidative species, such as the intracellular milieu of cancer cells, the main absorption band of spherical, water-soluble polyaniline nanoparticles was red-shifted to a near-infrared (NIR) wavelength as a result of the formation of the emeraldine salt (see picture). The doped nanoparticles caused photothermal ablation of cancer cells upon NIR laser irradiation in vitro and in vivo.

AB - Infiltrate and destroy: In an environment rich in protonating or oxidative species, such as the intracellular milieu of cancer cells, the main absorption band of spherical, water-soluble polyaniline nanoparticles was red-shifted to a near-infrared (NIR) wavelength as a result of the formation of the emeraldine salt (see picture). The doped nanoparticles caused photothermal ablation of cancer cells upon NIR laser irradiation in vitro and in vivo.

KW - cancer

KW - nanoparticles

KW - near-infrared light

KW - photothermal agents

KW - polymers

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U2 - 10.1002/anie.201005075

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SN - 1433-7851

VL - 50

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JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 2

ER -

Convertible organic nanoparticles for near-infrared photothermal ablation of cancer cells

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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