Abstract
Core/shell nanoparticles (NPs) are formed using various strategies and offer considerable advantages for diagnosis and therapy. Because of the hydrophilic nature of their shell with relatively small size, core/shell NPs have been utilized to solubilize hydrophobic drugs as well as imaging agents, improving pharmacokinetics. This chapter will introduce various types of core/shell NPs based on their preparation method and formation mechanism. The focus will be on the core/shell nanomedicine for tumor targeting, stimulated release of proteins, and cancer imaging capabilities.
Original language | English |
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Title of host publication | Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering |
Publisher | John Wiley and Sons |
Pages | 321-343 |
Number of pages | 23 |
ISBN (Print) | 9781118290323 |
DOIs | |
Publication status | Published - 2013 Feb 18 |
Keywords
- Core/shell nanoparticles
- Drug delivery system
- Molecular imaging
- Polymeric micelle
- Temperature induced phase transition
ASJC Scopus subject areas
- Medicine(all)
- Engineering(all)